Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26205631 | 0.84 | MAPT (0.44) | MAPTADRB2ADRB1ALDH1A1KDM4E | |
| SCHEMBL20898309 | 0.78 | MAPT (0.60) | MAPTHPGDALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL23163644 | 0.76 | KDM4E (0.49) | MAPTKDM4ETDP1MAPK1GPR88 | |
| SCHEMBL7749771 | 0.75 | MAPT (0.51) | MAPTHPGDALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL28062700 | 0.75 | HPGD (0.51) | MAPTHPGDALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7191065 | 0.75 | MAOB (0.40) | MAPTALDH1A1KDM4ESMN1; SMN2GPR88 | |
| SCHEMBL4115419 | 0.74 | PTGS2 (0.57) | MAPTALDH1A1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL14883463 | 0.74 | HDAC1 (0.51) | MAPTHPGDALDH1A1KDM4EGAA | |
| SCHEMBL21991589 | 0.73 | MAPT (0.49) | MAPTHPGDALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL25377756 | 0.72 | GPR88 (0.51) | ALDH1A1GPR88 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170327457-A1 | PHENYL-(AZA)CYCLOALKYL CARBOXYLIC ACID GPR120 MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2017-11-16 | — | — | US | disclosed |
| US-20170253554-A1 | CYCLOPROPANECARBOXYLIC ACID GPR120 MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2017-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170253554-A1 | CYCLOPROPANECARBOXYLIC ACID GPR120 MODULATORS | GPR88, GPBAR1, GPR68 | MAPT 4319/4885HPGD 956/4885ADRB2 66/4885 |
| US-20170327457-A1 | PHENYL-(AZA)CYCLOALKYL CARBOXYLIC ACID GPR120 MODULATORS | GPR88, GPR55, GPR180 | MAPT 4401/4885HPGD 1231/4885ADRB2 70/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.