Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14189823 | 0.86 | RAB9A (0.46) | KDM4EHSD17B10RAB9ANPC1ALDH1A1 | |
| SCHEMBL4799225 | 0.85 | NPC1 (0.45) | KDM4ERAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL16892757 | 0.84 | LMNA (0.50) | KDM4EHSD17B10RAB9ANPC1ALDH1A1 | |
| SCHEMBL14973037 | 0.84 | RAB9A (0.44) | KDM4ERAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL2192830 | 0.83 | CYP1A2 (0.40) | KDM4EHSD17B10RAB9ANPC1ALDH1A1 | |
| SCHEMBL10490542 | 0.80 | RAB9A (0.48) | KDM4EHSD17B10RAB9ANPC1ALDH1A1 | |
| SCHEMBL25368632 | 0.79 | NPC1 (0.46) | KDM4EHSD17B10RAB9ANPC1ALDH1A1 | |
| SCHEMBL8573566 | 0.79 | RAB9A (0.50) | KDM4ERAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL24884175 | 0.79 | CYP3A4 (0.44) | KDM4EHSD17B10RAB9ANPC1ALDH1A1 | |
| SCHEMBL24504529 | 0.78 | KDM4E (0.42) | KDM4EHSD17B10RAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119823045-A | Synthesis method of 3-difluoromethyl-1-methylpyrazole-4-ethyl formate | 湖南化工研究院有限公司 | 2025-04-15 | — | — | CN | claimed |
| CN-115819346-A | Synthetic method of 3- (difluoromethyl) -1-methyl-1H-pyrazole-4-ethyl formate | 湖南化工研究院有限公司 | 2023-03-21 | — | — | CN | claimed |
| CN-119823044-A | Preparation method of 3- (difluoromethyl) -1-methyl-1H-pyrazole-4-carboxylic acid ethyl ester | 湖南化工研究院有限公司 | 2025-04-15 | — | — | CN | disclosed |
| CN-119823045-A | Synthesis method of 3-difluoromethyl-1-methylpyrazole-4-ethyl formate | 湖南化工研究院有限公司 | 2025-04-15 | — | — | CN | disclosed |
| CN-119039225-A | Purification method of fluorine-containing methyl pyrazole carboxylic ester | 中蓝晨光化工研究设计院有限公司 | 2024-11-29 | — | — | CN | disclosed |
| CN-115819346-A | Synthetic method of 3- (difluoromethyl) -1-methyl-1H-pyrazole-4-ethyl formate | 湖南化工研究院有限公司 | 2023-03-21 | — | — | CN | disclosed |
| CN-106467492-B | preparation method of polyfluoromethyl pyrazole compound, intermediate and preparation method | 联化科技(盐城)有限公司 | 2019-12-17 | — | — | CN | disclosed |
| US-20180208559-A1 | PROCESS FOR THE PREPARATION OF 3-HALOALKYLPYRAZOLES | Syngental Participations AG (CH) | 2018-07-26 | — | — | US | disclosed |
| US-20180208559-A1 | PROCESS FOR THE PREPARATION OF 3-HALOALKYLPYRAZOLES | Syngental Participations AG (CH) | 2018-07-26 | — | — | US | disclosed |
| US-9926279-B2 | Process for the preparation of 3-haloalkylpyrazoles | SYNGENTA PARTICIPATIONS AG (CH) | 2018-03-27 | — | — | US | disclosed |
| US-9926279-B2 | Process for the preparation of 3-haloalkylpyrazoles | SYNGENTA PARTICIPATIONS AG (CH) | 2018-03-27 | — | — | US | disclosed |
| US-20100204483-A1 | PROCESS FOR PREPARING 2-DIHALOACYL-3-AMINOACRYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-08-12 | — | — | US | disclosed |
| WO-2010009990-A1 | PROCESS FOR PREPARING 1,3-DISUBSTITUTED PYRAZOLECARBOXYLIC ESTERS | BASF SE (DE) | 2010-01-28 | — | — | WO | disclosed |
| WO-2009043444-A1 | PROCESS FOR PREPARING 2-DIHALOACYL-3-AMINOACRYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2009-04-09 | — | — | WO | disclosed |
| EP-2042482-A1 | Method for manufacturing 2-dihalogenacyl-3-amino-acrylic acid derivatives | Bayer CropScience AG (DE) | 2009-04-01 | — | — | EP | disclosed |
| US-20080154045-A1 | Process for Producing 1-Substituted-3-Fluoroalkylpyrazole-4-Carboxylate | SAGAMI CHEMICAL RESEARCKH CENTER (JP) | 2008-06-26 | — | — | US | disclosed |
| US-7358387-B2 | Method for producing 2-dihaloacyl-3-amino-acrylic acid esters and 3-dihalomethyl pyrazole-4-carboxylic acid esters | BAYER CROPSCIENCE AG (DE) | 2008-04-15 | — | — | US | disclosed |
| US-7358387-B2 | Method for producing 2-dihaloacyl-3-amino-acrylic acid esters and 3-dihalomethyl pyrazole-4-carboxylic acid esters | BAYER CROPSCIENCE AG (DE) | 2008-04-15 | — | — | US | disclosed |
| EP-1854788-A1 | METHOD FOR PRODUCING 1-SUBSTITUTED-3-FLUOROALKYL PYRAZOLE-4-CARBOXYLATE | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2007-11-14 | — | — | EP | disclosed |
| US-20060252944-A1 | Method for producing 2-dihaloacyl-3-amino-acrylic acid esters and 3-dihalomethyl pyrazole-4-carboxylic acid esters | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2006-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180208559-A1 | PROCESS FOR THE PREPARATION OF 3-HALOALKYLPYRAZOLES | F9, CYP4F3, CYP2C9 | KDM4E 342/4885HSD17B10 2093/4885RAB9A 78/4885 |
| US-20100204483-A1 | PROCESS FOR PREPARING 2-DIHALOACYL-3-AMINOACRYLIC ACID DERIVATIVES | AADAT, DDC, IDUA | KDM4E 3237/4885HSD17B10 4204/4885RAB9A 1035/4885 |
| US-20060252944-A1 | Method for producing 2-dihaloacyl-3-amino-acrylic acid esters and 3-dihalomethyl pyrazole-4-carboxylic acid esters | DDC, IDUA, AADAT | KDM4E 3328/4885HSD17B10 1455/4885RAB9A 2779/4885 |
| US-20080154045-A1 | Process for Producing 1-Substituted-3-Fluoroalkylpyrazole-4-Carboxylate | CYP4Z1, CYP3A4, HACL2 | KDM4E 1021/4885HSD17B10 603/4885RAB9A 1714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.