Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ATR | Q13535 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20607635 | 0.90 | DDR1 (0.35) | — | |
| SCHEMBL32678388 | 0.80 | KCNH2 (0.33) | — | |
| SCHEMBL32678389 | 0.80 | KCNH2 (0.33) | — | |
| SCHEMBL25315137 | 0.77 | UTRN (0.43) | MAPT | |
| SCHEMBL30989624 | 0.77 | UTRN (0.43) | MAPT | |
| SCHEMBL23120266 | 0.76 | UTRN (0.36) | TP53MAPT | |
| SCHEMBL29543511 | 0.76 | UTRN (0.36) | TP53MAPT | |
| SCHEMBL23136589 | 0.76 | UTRN (0.41) | MAPT | |
| SCHEMBL32678416 | 0.75 | UTRN (0.39) | MAPT | |
| SCHEMBL17231835 | 0.75 | PTGS2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200055850-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-02-20 | — | — | US | claimed |
| US-20170260182-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-14 | — | — | US | claimed |
| US-20200055850-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-02-20 | — | — | US | disclosed |
| US-10435401-B2 | Pesticidally active tetracyclic derivatives with sulphur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2019-10-08 | — | — | US | disclosed |
| EP-3194394-B1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-01-09 | — | — | EP | disclosed |
| US-20170260182-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170260182-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | DDT, ACHE, GSTO1 | TP53 4639/4885MAPT 643/4885ATR 2379/4885 |
| US-20200055850-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | DDT, ACHE, GSTM1 | TP53 4671/4885MAPT 735/4885ATR 2191/4885 |
| US-10435401-B2 | Pesticidally active tetracyclic derivatives with sulphur containing substituents | DDT, ACHE, GSTO1 | TP53 4639/4885MAPT 643/4885ATR 2379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.