Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 9/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19327405 | 0.90 | TP53 (0.31) | — | |
| SCHEMBL17231835 | 0.86 | PTGS2 (0.36) | DDR1ALOX5APFEN1ALDH1A1 | |
| SCHEMBL29431630 | 0.85 | LMNA (0.33) | DDR1ALOX5APFEN1ALDH1A1LMNA | |
| SCHEMBL20607634 | 0.85 | UTRN (0.40) | DDR1 | |
| SCHEMBL15858547 | 0.85 | LMNA (0.33) | DDR1ALOX5APFEN1ALDH1A1LMNA | |
| SCHEMBL17231834 | 0.83 | DDR1 (0.30) | DDR1 | |
| SCHEMBL15933505 | 0.83 | — | — | |
| SCHEMBL17986902 | 0.81 | HDAC6 (0.32) | LMNACNR2 | |
| SCHEMBL29431583 | 0.80 | DDR1 (0.36) | DDR1LMNAS1PR1 | |
| SCHEMBL15933389 | 0.80 | DDR1 (0.36) | DDR1LMNAS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200055850-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-02-20 | — | — | US | claimed |
| CN-106715428-B | Pesticidally active tetracyclic derivatives with sulfur-containing substituents | 先正达参股股份有限公司 | 2020-07-07 | — | — | CN | disclosed |
| US-20200055850-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-02-20 | — | — | US | disclosed |
| US-10435401-B2 | Pesticidally active tetracyclic derivatives with sulphur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2019-10-08 | — | — | US | disclosed |
| EP-3194394-B1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-01-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055850-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | DDT, ACHE, GSTM1 | DDR1 4290/4885PLA2G1B 1521/4885ATG4B 2669/4885 |
| US-10435401-B2 | Pesticidally active tetracyclic derivatives with sulphur containing substituents | DDT, ACHE, GSTO1 | DDR1 4051/4885PLA2G1B 1441/4885ATG4B 2813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.