Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11477697 | 0.98 | ALDH1A1 (0.57) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9165319 | 0.87 | ALDH1A1 (0.49) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22062215 | 0.85 | GAA (0.49) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22062268 | 0.82 | TDP1 (0.50) | ALDH1A1MAPTSMN1; SMN2NPC1GAA | |
| SCHEMBL22062252 | 0.81 | CA1 (0.42) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL16275070 | 0.81 | SMN1; SMN2 (0.53) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22062220 | 0.80 | TDP1 (0.53) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL22062177 | 0.80 | HDAC3 (0.53) | ALDH1A1MAPTKMT2ACYP19A1 | |
| SCHEMBL9397945 | 0.80 | ALDH1A1 (0.62) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL97859 | 0.80 | ALDH1A1 (0.73) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11279677-B2 | Photochromic hydrazone switches | THE TRUSTEES OF DARTMOUTH COLLEGE (US) | 2022-03-22 | — | — | US | disclosed |
| EP-3580207-B1 | DIAZOMETHYLATION REAGENT AND PROCESS FOR USING IT | FUNDACIO PRIVADA INSTITUT CATALA DINVESTIGACIO QUIM ICIQ (ES) | 2020-11-11 | — | — | EP | disclosed |
| US-10676427-B2 | Diazomethylation reagent and process for using it | FUNDACIÓ INSTITUT CATALÀ D'INVESTIGACIÓ QUÍMICA (ICIQ) (ES) | 2020-06-09 | — | — | US | disclosed |
| US-20190256472-A1 | PHOTOCHROMIC HYDRAZONE SWITCHES | DARTMOUTH COLLEGE (US) | 2019-08-22 | — | — | US | disclosed |
| US-9760003-B2 | Pattern forming method and actinic-ray- or radiation-sensitive resin composition | FUJIFILM CORPORATION (JP) | 2017-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10676427-B2 | Diazomethylation reagent and process for using it | DDT, DDC, CYP2E1 | ALDH1A1 189/4885MAPT 4461/4885MEN1 779/4885 |
| US-20190256472-A1 | PHOTOCHROMIC HYDRAZONE SWITCHES | CRYZ, PIN1, PPOX | ALDH1A1 404/4885MAPT 702/4885MEN1 2778/4885 |
| US-11279677-B2 | Photochromic hydrazone switches | CRYZ, PIN1, PPOX | ALDH1A1 404/4885MAPT 702/4885MEN1 2778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.