Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16840087 | 0.86 | PKM (0.45) | MAPTPKMSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL16840071 | 0.82 | GPR139 (0.42) | MAPTPKMSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL2119361 | 0.81 | CYP2D6 (0.46) | MAPTPKMSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL7303575 | 0.81 | CYP2D6 (0.46) | MAPTPKMSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL16840085 | 0.79 | L3MBTL1 (0.39) | MAPTPKMSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL19716698 | 0.78 | EPHX1 (0.51) | LMNASLC6A3 | |
| SCHEMBL11262314 | 0.74 | MAPT (0.47) | MAPTPKMSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL3056114 | 0.72 | SLC6A3 (0.47) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL1959777 | 0.71 | TSHR (0.46) | MAPTLMNATSHRMEN1KMT2A | |
| SCHEMBL10728103 | 0.71 | PTGS2 (0.48) | GAATRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9758606-B2 | Cyclopropenium polymers and methods for making the same | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-09-12 | — | — | US | disclosed |