Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 2/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.33 |
| ▸ | ADK | P55263 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 3/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | PRCP | P42785 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19336697 | 0.94 | L3MBTL1 (0.35) | DRD2SMN1; SMN2HTR1AHTR7DRD1 | |
| SCHEMBL19336698 | 0.86 | JAK2 (0.38) | SMN1; SMN2SRD5A1HSD17B10LMNATP53 | |
| SCHEMBL19336713 | 0.86 | SMN1; SMN2 (0.34) | SMN1; SMN2HTR1AHTR7SRD5A1GSK3B | |
| SCHEMBL17952985 | 0.85 | DRD2 (0.34) | DRD2SMN1; SMN2HTR1AHTR7DRD1 | |
| SCHEMBL19337843 | 0.84 | ROCK1 (0.37) | SMN1; SMN2SRD5A1MEN1ALDH1A1KMT2A | |
| SCHEMBL17082306 | 0.84 | HTR1A (0.33) | DRD2SMN1; SMN2HTR1AHTR7DRD1 | |
| SCHEMBL19336702 | 0.82 | PKM (0.35) | DRD2SMN1; SMN2HTR1AHTR7DRD1 | |
| SCHEMBL17082245 | 0.82 | DRD2 (0.32) | DRD2SMN1; SMN2HTR1AHTR7DRD1 | |
| SCHEMBL19336701 | 0.81 | L3MBTL1 (0.33) | SMN1; SMN2HTR1AHTR7MAPK1ALDH1A1 | |
| SCHEMBL19336699 | 0.80 | ALDH1A1 (0.37) | SMN1; SMN2HSD17B10LMNAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2918591-B1 | NOVEL LIGAND COMPOUND, PREPARATION METHOD THEREFOR, TRANSITION METAL COMPOUND, AND PREPARATION METHOD THEREFOR | LG CHEMICAL LTD (KR) | 2017-09-13 | — | — | EP | disclosed |