Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGF1 | P05230 | 2/20 | 0.40 |
| ▸ | ENGASE | Q8NFI3 | 1/20 | 0.39 |
| ▸ | AMY2A | P04746 | 4/20 | 0.39 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.38 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.38 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.38 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.38 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.38 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.38 |
| ▸ | CD209 | Q9NNX6 | 1/20 | 0.37 |
| ▸ | GJB2 | P29033 | 4/20 | 0.36 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | MGAM | O43451 | 2/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24436935 | 0.96 | FGF1 (0.39) | FGF1ENGASEAMY2ALGALS3LGALS9 | |
| SCHEMBL19350572 | 0.89 | ENGASE (0.36) | ENGASEAMY2ALGALS3LGALS8LGALS4 | |
| SCHEMBL19350516 | 0.85 | GJB2 (0.35) | ENGASEAMY2ALGALS3LGALS8LGALS4 | |
| SCHEMBL15686020 | 0.84 | AMY2A (0.43) | ENGASEAMY2ALGALS3LGALS9LGALS1 | |
| SCHEMBL20859590 | 0.84 | AMY2A (0.43) | ENGASEAMY2ALGALS3LGALS9LGALS1 | |
| SCHEMBL19213283 | 0.84 | SSTR1 (0.36) | FGF1LGALS8GJB2 | |
| SCHEMBL23709922 | 0.84 | FGF1 (0.35) | FGF1ENGASEAMY2ALGALS3LGALS9 | |
| SCHEMBL14925559 | 0.83 | GJB2 (0.39) | FGF1ENGASEAMY2ALGALS3LGALS9 | |
| SCHEMBL23306563 | 0.81 | AMY1A (0.45) | FGF1ENGASEAMY2ALGALS3LGALS9 | |
| SCHEMBL14327697 | 0.81 | AMY2A (0.41) | AMY2ALGALS3LGALS8LGALS4GJB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170258832-A1 | Therapeutic Detoxification Compositions and Methods of Making and Using Same | ImMutriX Therapeutics, Inc. | 2017-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170258832-A1 | Therapeutic Detoxification Compositions and Methods of Making and Using Same | OAT, MSR1, GSTA2 | FGF1 2603/4885ENGASE 942/4885AMY2A 1500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.