Sugi Predict

Sugi Predict / Compounds / SCHEMBL193441

SCHEMBL193441

SCHEMBL193441

N#Cc1cc(-c2ccccc2F)[nH]c1Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP11B2 P19099 2/20 0.40
▸ CYP11B1 P15538 1/20 0.40
▸ AR P10275 2/20 0.39
▸ ALDH1A1 P00352 2/20 0.38
▸ KDM4E B2RXH2 1/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ GLA P06280 1/20 0.38
▸ GAA P10253 1/20 0.38
▸ HPGD P15428 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ CUL4A Q13619 1/20 0.37
▸ CHUK O15111 1/20 0.37
▸ ADORA2A P29274 1/20 0.36
▸ ADORA1 P30542 1/20 0.36
▸ NPC1 O15118 1/20 0.35
▸ MTOR P42345 1/20 0.35
▸ USP8 P40818 1/20 0.34
▸ USP7 Q93009 1/20 0.34
▸ ESR2 Q92731 1/20 0.34
▸ BCAT1 P54687 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29519753 1.00 CYP11B2 (0.40) CYP11B2CYP11B1ARALDH1A1KDM4E
SCHEMBL20952245 0.88 CHUK (0.36) CYP11B2CYP11B1ARALDH1A1KDM4E
SCHEMBL193697 0.80 FFAR1 (0.33) ALDH1A1MEN1HPGDKMT2ANPC1
SCHEMBL194590 0.79 CYP11B1 (0.43) CYP11B2CYP11B1ARALDH1A1KDM4E
SCHEMBL29815753 0.79 CYP11B1 (0.43) CYP11B2CYP11B1ARALDH1A1KDM4E
SCHEMBL7820572 0.76 MAOA (0.47) ALDH1A1KDM4EMEN1GLAGAA
SCHEMBL193577 0.74 CDC7 (0.40) CYP11B2CYP11B1ARADORA2AADORA1
SCHEMBL21757303 0.73 CYP11B1 (0.38) CYP11B2CYP11B1ARALDH1A1KDM4E
SCHEMBL2650416 0.73 ESR2 (0.48) CYP11B2CYP11B1ALDH1A1KDM4EHPGD
SCHEMBL22115306 0.71 CYP11B2 (0.43) CYP11B2CYP11B1ARALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113511995-B Preparation method of 5- (2-fluorophenyl) -1H-pyrrole-3-formaldehyde 四川科伦药物研究院有限公司 2024-07-09 — — CN claimed
CN-117030876-A Method for detecting related substances of Fu Nuola raw starting material of fumaric acid 山东新华制药股份有限公司 2023-11-10 — — CN claimed
CN-113511995-A Preparation method of 5- (2-fluorophenyl) -1H-pyrrole-3-formaldehyde 四川科伦药物研究院有限公司 2021-10-19 — — CN claimed
CN-112194607-A Synthetic method of 5- (2-fluorophenyl) -1H-pyrrole-3-formaldehyde 河北科博莱特医药科技有限公司 2021-01-08 — — CN claimed
US-12351553-B2 Process for producing 5-aryl-1H-pyrolle-3-carbonitrile compounds by dehalogenation TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2025-07-08 — — US disclosed
CN-113511995-B Preparation method of 5- (2-fluorophenyl) -1H-pyrrole-3-formaldehyde 四川科伦药物研究院有限公司 2024-07-09 — — CN disclosed
CN-113511995-B Preparation method of 5- (2-fluorophenyl) -1H-pyrrole-3-formaldehyde 四川科伦药物研究院有限公司 2024-07-09 — — CN disclosed
CN-118108652-A Preparation method of 5- (2-fluorophenyl) -1H-pyrrole-3-carbonitrile 中山奕安泰医药科技有限公司 2024-05-31 — — CN disclosed
CN-117030876-A Method for detecting related substances of Fu Nuola raw starting material of fumaric acid 山东新华制药股份有限公司 2023-11-10 — — CN disclosed
CN-117030876-A Method for detecting related substances of Fu Nuola raw starting material of fumaric acid 山东新华制药股份有限公司 2023-11-10 — — CN disclosed
US-20230088365-A1 PROCESS FOR PRODUCING PYRROLE COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-03-23 — — US disclosed
US-11498898-B2 Process for producing pyrrole compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2022-11-15 — — US disclosed
EP-2402313-B1 PROCESS FOR PRODUCING PYRROLE COMPOUND TAKEDA PHARMACEUTICAL (JP) 2016-08-24 — — EP disclosed
US-9266831-B2 Process for producing pyrrole compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-02-23 — — US disclosed
US-20140303378-A1 PROCESS FOR PRODUCING PYRROLE COMPOUND TAKEDA PHARMACEUTICAL (JP) 2014-10-09 — — US disclosed
US-8822694-B2 Process for producing pyrrole compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2014-09-02 — — US disclosed
EP-2765130-A2 Process for producing pyrrole compound Takeda Pharmaceutical Company Limited (JP) 2014-08-13 — — EP disclosed
CN-102421753-A Process for preparing azole compounds TAKEDA PHARMACEUTICAL 2012-04-18 — — CN disclosed
EP-2402313-A1 PROCESS FOR PRODUCING PYRROLE COMPOUND Takeda Pharmaceutical Company Limited (JP) 2012-01-04 — — EP disclosed
US-20110306769-A1 PROCESS FOR PRODUCING PYRROLE COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2011-12-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12351553-B2 Process for producing 5-aryl-1H-pyrolle-3-carbonitrile compounds by dehalogenation CYP51A1, PAH, HPD CYP11B2 67/4885CYP11B1 37/4885AR 4098/4885
US-20230088365-A1 PROCESS FOR PRODUCING PYRROLE COMPOUND DHPS, STS, HPD CYP11B2 460/4885CYP11B1 656/4885AR 4253/4885
US-11498898-B2 Process for producing pyrrole compound DHPS, STS, HPD CYP11B2 460/4885CYP11B1 656/4885AR 4253/4885
US-20140303378-A1 PROCESS FOR PRODUCING PYRROLE COMPOUND DHPS, STS, HPD CYP11B2 460/4885CYP11B1 656/4885AR 4253/4885
US-20110306769-A1 PROCESS FOR PRODUCING PYRROLE COMPOUND DHPS, STS, HPD CYP11B2 460/4885CYP11B1 656/4885AR 4253/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.