Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | GLA | P06280 | 1/20 | 0.72 |
| ▸ | P2RY2 | P41231 | 5/20 | 0.62 |
| ▸ | ST6GAL1 | P15907 | 9/20 | 0.58 |
| ▸ | P2RY6 | Q15077 | 4/20 | 0.56 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citicoline SCHEMBL31413926 | 0.99 | TSHR (0.73) | TSHRGLAP2RY2ST6GAL1P2RY6 | |
| Citicoline SCHEMBL221081 | 0.99 | TSHR (0.73) | TSHRGLAP2RY2ST6GAL1P2RY6 | |
| Citicoline SCHEMBL50799 | 0.99 | TSHR (0.73) | TSHRGLAP2RY2ST6GAL1P2RY6 | |
| Citicoline SCHEMBL31554836 | 0.99 | TSHR (0.73) | TSHRGLAP2RY2ST6GAL1P2RY6 | |
| Citicoline SCHEMBL21906414 | 0.97 | TSHR (0.70) | TSHRGLAP2RY2ST6GAL1P2RY6 | |
| Citicoline SCHEMBL25411862 | 0.96 | TSHR (0.76) | TSHRGLAP2RY2ST6GAL1P2RY6 | |
| Citicoline SCHEMBL4311534 | 0.96 | TSHR (0.76) | TSHRGLAP2RY2ST6GAL1P2RY6 | |
| Citicoline SCHEMBL667104 | 0.93 | TSHR (0.84) | TSHRGLAP2RY2ST6GAL1P2RY6 | |
| Citicoline SCHEMBL14235352 | 0.92 | P2RY2 (0.70) | TSHRGLAP2RY2ST6GAL1P2RY6 | |
| Citicoline SCHEMBL13933086 | 0.92 | P2RY2 (0.70) | TSHRGLAP2RY2ST6GAL1P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4190319-A1 | PHARMACEUTICAL COMPOSITION COMPRISING MEMANTINE AND CITICOLINE | Novamedica Limited Liability Company (RU) | 2023-06-07 | — | — | EP | claimed |
| CN-114057813-A | Method for synthesizing sodium citicoline | 新乡拓新药业股份有限公司 | 2022-02-18 | — | — | CN | claimed |
| CN-110684066-B | Cytophosphocholine medicinal preparation and new application thereof in cerebral infarction acute-stage disturbance of consciousness | 广东金城金素制药有限公司 | 2020-12-08 | — | — | CN | claimed |
| CN-110684066-A | Cytophosphocholine medicinal preparation and new application thereof in cerebral infarction acute-stage disturbance of consciousness | 广东金城金素制药有限公司 | 2020-01-14 | — | — | CN | claimed |
| CN-117924395-A | Preparation, separation and detection method and application of citicoline sodium impurity with structure of formula I | 福建省闽东力捷迅药业股份有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-117924396-A | Citicoline sodium impurity, preparation method, separation detection method and application thereof | 福建省闽东力捷迅药业股份有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-113769794-B | Ion exchange system and method for continuously removing impurities in citicoline sodium | 沁浩膜技术(厦门)有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-117679518-A | Pharmaceutical composition for preventing and treating convalescence facial paralysis and application thereof | 北京达尔文细胞生物科技有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-117679519-A | Pharmaceutical composition for preventing and treating acute facial paralysis and application thereof | 北京达尔文细胞生物科技有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-117679522-A | Pharmaceutical composition for preventing and treating nervous system lesions and application thereof | 北京达尔文细胞生物科技有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-117045613-A | Pharmaceutical composition for treating diabetic peripheral neuropathy and preparation method thereof | 重庆康刻尔制药股份有限公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-116790466-B | Method for producing citicoline by engineering bacillus subtilis fermentation | 山东理工大学 | 2023-11-03 | — | — | CN | disclosed |
| CN-114057813-A | Method for synthesizing sodium citicoline | 新乡拓新药业股份有限公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-110684066-B | Cytophosphocholine medicinal preparation and new application thereof in cerebral infarction acute-stage disturbance of consciousness | 广东金城金素制药有限公司 | 2020-12-08 | — | — | CN | disclosed |
| CN-110684066-B | Cytophosphocholine medicinal preparation and new application thereof in cerebral infarction acute-stage disturbance of consciousness | 广东金城金素制药有限公司 | 2020-12-08 | — | — | CN | disclosed |
| CN-107496369-B | Citicoline sodium tablet and direct powder tabletting preparation method thereof | 福建省闽东力捷迅药业有限公司 | 2020-06-26 | — | — | CN | disclosed |
| CN-110684066-A | Cytophosphocholine medicinal preparation and new application thereof in cerebral infarction acute-stage disturbance of consciousness | 广东金城金素制药有限公司 | 2020-01-14 | — | — | CN | disclosed |
| CN-110684066-A | Cytophosphocholine medicinal preparation and new application thereof in cerebral infarction acute-stage disturbance of consciousness | 广东金城金素制药有限公司 | 2020-01-14 | — | — | CN | disclosed |
| EP-3219306-A1 | COMPOSITION FOR PREVENTING AND TREATING NEUODEGENERATIVE DISEASES AD COGNITIVE DISORDERS | FB HEALTH S.P.A. (IT) | 2017-09-20 | — | — | EP | disclosed |
| CN-1513468-A | Compound medicine of sodium citicoline and disodium cytidine triphosphate | 杨喜鸿 | 2004-07-21 | — | — | CN | disclosed |