Citicoline

Citicoline

SCHEMBL25411862

C[N+](C)(C)CCOP(=O)(O)OP(=O)([O-])OC[C@H]1O[C@@H](n2ccc(N)nc2=O)[C@@H](O)[C@@H]1O

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.76
GLA P06280 1/20 0.76
P2RY2 P41231 5/20 0.61
ST6GAL1 P15907 10/20 0.61
P2RY4 P51582 3/20 0.57
P2RY6 Q15077 3/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Citicoline SCHEMBL4311534 1.00 TSHR (0.76) TSHRGLAP2RY2ST6GAL1P2RY4
Citicoline SCHEMBL50799 0.97 TSHR (0.73) TSHRGLAP2RY2ST6GAL1P2RY4
Citicoline SCHEMBL31554836 0.97 TSHR (0.73) TSHRGLAP2RY2ST6GAL1P2RY4
Citicoline SCHEMBL31413926 0.97 TSHR (0.73) TSHRGLAP2RY2ST6GAL1P2RY4
Citicoline SCHEMBL221081 0.97 TSHR (0.73) TSHRGLAP2RY2ST6GAL1P2RY4
Citicoline SCHEMBL19347200 0.96 TSHR (0.72) TSHRGLAP2RY2ST6GAL1P2RY4
Citicoline SCHEMBL21906414 0.94 TSHR (0.70) TSHRGLAP2RY2ST6GAL1P2RY4
Citicoline SCHEMBL667104 0.93 TSHR (0.84) TSHRGLAP2RY2ST6GAL1P2RY4
Citicoline SCHEMBL13933086 0.93 P2RY2 (0.70) TSHRGLAP2RY2ST6GAL1P2RY4
Citicoline SCHEMBL14235352 0.93 P2RY2 (0.70) TSHRGLAP2RY2ST6GAL1P2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12551475-B2 Methods and compositions for treating RNA viral infections MODEL MEDICINES, INC. (US) 2026-02-17 US disclosed
EP-4667008-A2 METHODS AND COMPOSITIONS FOR TREATING RNA VIRAL INFECTIONS Model Medicines, Inc. (US) 2025-12-24 EP disclosed
US-20230248712-A1 METHODS AND COMPOSITIONS FOR TREATING RNA VIRAL INFECTIONS MODEL MEDICINES, INC. 2023-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12551475-B2 Methods and compositions for treating RNA viral infections SARS1, EIF2AK2, SNRPE TSHR 1607/4885GLA 4255/4885P2RY2 435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.