Citicoline

Citicoline

SCHEMBL4311534

C[N+](C)(C)CCOP(=O)(O)OP(=O)([O-])OC[C@H]1O[C@@H](n2ccc(N)nc2=O)[C@H](O)[C@@H]1O

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.76
GLA P06280 1/20 0.76
P2RY2 P41231 5/20 0.61
ST6GAL1 P15907 10/20 0.61
P2RY4 P51582 3/20 0.57
P2RY6 Q15077 3/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Citicoline SCHEMBL25411862 1.00 TSHR (0.76) TSHRGLAP2RY2ST6GAL1P2RY4
Citicoline SCHEMBL50799 0.97 TSHR (0.73) TSHRGLAP2RY2ST6GAL1P2RY4
Citicoline SCHEMBL31554836 0.97 TSHR (0.73) TSHRGLAP2RY2ST6GAL1P2RY4
Citicoline SCHEMBL31413926 0.97 TSHR (0.73) TSHRGLAP2RY2ST6GAL1P2RY4
Citicoline SCHEMBL221081 0.97 TSHR (0.73) TSHRGLAP2RY2ST6GAL1P2RY4
Citicoline SCHEMBL19347200 0.96 TSHR (0.72) TSHRGLAP2RY2ST6GAL1P2RY4
Citicoline SCHEMBL21906414 0.94 TSHR (0.70) TSHRGLAP2RY2ST6GAL1P2RY4
Citicoline SCHEMBL667104 0.93 TSHR (0.84) TSHRGLAP2RY2ST6GAL1P2RY4
Citicoline SCHEMBL13933086 0.93 P2RY2 (0.70) TSHRGLAP2RY2ST6GAL1P2RY4
Citicoline SCHEMBL14235352 0.93 P2RY2 (0.70) TSHRGLAP2RY2ST6GAL1P2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 552 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250205241-A1 COMPOSITIONS AND METHODS FOR MINIMIZING EFFECTS OF ALCOHOL INTOXICATION SAFETY SHOT, INC. (US) 2025-06-26 US claimed
WO-2025136556-A1 COMPOSITIONS AND METHODS FOR MINIMIZING EFFECTS OF ALCOHOL INTOXICATION SAFETY SHOT, INC. (US) 2025-06-26 WO claimed
US-20250170246-A1 CDP-CHOLINE A HOST-DIRECTED THERAPEUTIC FOR DISEASE CAUSED BY SARS COV-2 INFECTION OHIO STATE INNOVATION FOUNDATION 2025-05-29 US claimed
EP-4072336-B1 ORAL PRODUCTS NICOVENTURES TRADING LTD (GB) 2025-04-09 EP claimed
WO-2025040605-A1 OPHTHALMOLOGICAL COMPOSITION CONTAINING AT LEAST ONE NICOTINIC ACETYLCHOLINE RECEPTOR MODULATOR FOR TOPICAL ADMINISTRATION TO THE EYE FOR PREVENTING OR TREATING INFLAMMATION OF THE EYE URSAPHARM ARZNEIMITTEL GMBH (DE) 2025-02-27 WO claimed
US-12156878-B1 Compositions and methods for minimizing effects of alcohol intoxication SAFETY SHOT, INC. (US) 2024-12-03 US claimed
EP-4072301-B1 A POUCH FOR ORAL USE COMPRISING A NANOEMULSION NICOVENTURES TRADING LTD (GB) 2024-11-06 EP claimed
CN-118647380-A Treatment of autism spectrum disorders with ergothioneine or ergoselen 自闭症治疗有限公司 2024-09-13 CN claimed
CN-118354774-A Parafurine-based caffeine surrogate compositions and methods of use thereof in caffeine slow metabolins PX ING有限责任公司 2024-07-16 CN claimed
US-20240188613-A1 SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF FIRMENICH INCORPORATED 2024-06-13 US claimed
WO-2022155669-A1 SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF FIRMENICH INCORPORATED (US) 2022-07-21 WO claimed
US-20220211720-A1 DIETARY SUPPLEMENT MORRISSETTE JAMES PETER (US) 2022-07-07 US claimed
US-11351181-B2 Dietary supplement KARMAGREEN, LLC 2022-06-07 US claimed
US-11337986-B2 Dietary supplement KARMAGREEN, LLC 2022-05-24 US claimed
US-20220152043-A1 DIETARY SUPPLEMENT MORRISSETTE JAMES PETER (US) 2022-05-19 US claimed
US-20220152042-A1 DIETARY SUPPLEMENT MORRISSETTE JAMES PETER (US) 2022-05-19 US claimed
US-11324755-B2 Dietary supplement KARMAGREEN, LLC 2022-05-10 US claimed
US-11324754-B2 Dietary supplement KARMAGREEN, LLC 2022-05-10 US claimed
EP-3137067-B1 CITICOLINE TO IMPROVE MOTOR FUNCTION KYOWA HAKKO BIO CO LTD (JP) 2022-05-04 EP claimed
US-20220062425-A1 LIPONUCLEOTIDE-BASED THERAPY FOR COPD OHIO STATE INNOVATION FOUNDATION 2022-03-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250170246-A1 CDP-CHOLINE A HOST-DIRECTED THERAPEUTIC FOR DISEASE CAUSED BY SARS COV-2 INFECTION CDS2, PHOSPHO1, PCYT1A TSHR 3893/4885GLA 2309/4885P2RY2 503/4885
US-20220062425-A1 LIPONUCLEOTIDE-BASED THERAPY FOR COPD PHOSPHO1, CHKB, CEPT1 TSHR 2345/4885GLA 1469/4885P2RY2 689/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.