Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 2/20 | 0.39 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | MDM4 | O15151 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 2/20 | 0.30 |
| ▸ | CNR2 | P34972 | 2/20 | 0.30 |
| ▸ | GPR3 | P46089 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19349124 | 1.00 | DUT (0.39) | DUTKIF11CYP1A2TSHRKCNN4 | |
| SCHEMBL436025 | 0.88 | KIF11 (0.34) | DUTKIF11TSHRKMT2AMEN1 | |
| SCHEMBL436023 | 0.88 | KIF11 (0.34) | DUTKIF11TSHRKMT2AMEN1 | |
| SCHEMBL8892535 | 0.83 | CYP1A2 (0.37) | CYP1A2TSHRKMT2AGPR3 | |
| SCHEMBL8893033 | 0.83 | CYP1A2 (0.37) | CYP1A2TSHRKMT2AGPR3 | |
| SCHEMBL25177898 | 0.83 | CYP1A2 (0.37) | CYP1A2TSHRKMT2AGPR3 | |
| SCHEMBL28486576 | 0.82 | CYP1A2 (0.36) | CYP1A2TSHRKMT2AGPR3 | |
| SCHEMBL16933112 | 0.82 | CYP1A2 (0.39) | CYP1A2TSHRKMT2ATP53GPR3 | |
| SCHEMBL14648233 | 0.82 | CYP1A2 (0.36) | CYP1A2TSHRKMT2AGPR3 | |
| SCHEMBL30510342 | 0.82 | CYP1A2 (0.36) | CYP1A2TSHRKMT2AGPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106715457-B | Small molecule targeting couplet specifically activated by tumor microenvironment and application thereof | 亚飞（上海）生物医药科技有限公司 | 2021-09-28 | — | — | CN | disclosed |
| US-20170266308-A1 | SMALL MOLECULE CONJUGATES SPECIFICALLY ACTIVATED IN TUMOR MICROENVIROMENT FOR TARGETING AND USE THEREOF | YAFEI SHANGHAI BIOLOG MEDICINE SCIENCE & TECHNOLOGY CO. LTD. (CN) | 2017-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170266308-A1 | SMALL MOLECULE CONJUGATES SPECIFICALLY ACTIVATED IN TUMOR MICROENVIROMENT FOR TARGETING AND USE THEREOF | CD4, MET, TNFSF10 | DUT 2501/4885KIF11 3636/4885CYP1A2 3022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.