Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ECE1 | P42892 | 2/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | MC5R | P33032 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19354510 | 1.00 | HTR2A (0.45) | HTR2AHTR2CHTR2BADRB2CYP1A2 | |
| SCHEMBL19354535 | 0.80 | IDO1 (0.43) | CYP1A2 | |
| SCHEMBL19354261 | 0.80 | IDO1 (0.43) | CYP1A2 | |
| SCHEMBL19354511 | 0.74 | SLC6A4 (0.41) | CYP1A2SLC6A4MEN1CYP2D6KMT2A | |
| SCHEMBL19354586 | 0.74 | SLC6A4 (0.41) | CYP1A2SLC6A4MEN1CYP2D6KMT2A | |
| SCHEMBL1247974 | 0.74 | CYP2D6 (0.46) | HTR2AHTR2CHTR2BCYP1A2CYP2A6 | |
| SCHEMBL15599121 | 0.71 | SIGMAR1 (0.47) | CYP1A2CYP2A6SLC6A4CYP2D6KMT2A | |
| SCHEMBL11748582 | 0.70 | HTR2A (0.67) | HTR2AHTR2CHTR2BADRB2CYP1A2 | |
| SCHEMBL5306693 | 0.70 | HTR2A (0.56) | HTR2AHTR2CHTR2BADRB2CYP1A2 | |
| SCHEMBL8465868 | 0.70 | HTR2A (0.67) | HTR2AHTR2CHTR2BADRB2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9765064-B1 | Alpha-hydroxy-beta-azido-tetrazoles | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2017-09-19 | — | — | US | disclosed |
| US-20170260171-A1 | ALPHA-HYDROXY-BETA-AZIDO-TETRAZOLES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2017-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170260171-A1 | ALPHA-HYDROXY-BETA-AZIDO-TETRAZOLES | CYP8B1, HSD3B1, HSD17B1 | HTR2A 1733/4885HTR2C 914/4885HTR2B 625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.