Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 2/20 | 0.38 |
| ▸ | GABRD | O14764 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetradecane SCHEMBL9931701 | 0.75 | ALDH1A1 (0.64) | CTSVCTSLKDM4EALDH1A1HPGD | |
| SCHEMBL24602915 | 0.73 | GABRP (0.39) | CTSVCTSLKDM4EALDH1A1HPGD | |
| SCHEMBL2356510 | 0.73 | CTSV (0.39) | CTSVCTSLKDM4EALDH1A1HPGD | |
| Carbazole SCHEMBL27757289 | 0.73 | ALDH1A1 (0.67) | CTSVCTSLKDM4EALDH1A1HPGD | |
| Carbazole SCHEMBL27643881 | 0.71 | ALDH1A1 (0.64) | CTSVCTSLKDM4EALDH1A1HPGD | |
| SCHEMBL28262029 | 0.71 | ALDH1A1 (0.41) | CTSVCTSLKDM4EALDH1A1HPGD | |
| SCHEMBL27878179 | 0.70 | KIF11 (0.45) | CTSVCTSLKDM4EALDH1A1HPGD | |
| SCHEMBL28342609 | 0.70 | KIF11 (0.45) | CTSVCTSLKDM4EALDH1A1HPGD | |
| SCHEMBL19055128 | 0.70 | VDR (0.53) | KDM4EALDH1A1HSD17B10UTS2RGAA | |
| SCHEMBL30302596 | 0.69 | KIF11 (0.44) | CTSVCTSLKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9765078-B2 | Compounds and methods for inhibiting mitotic progression | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2017-09-19 | — | — | US | disclosed |