Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19364701 | 0.81 | FDPS (0.48) | LMNASMN1; SMN2 | |
| SCHEMBL756357 | 0.81 | ALDH1A1 (0.41) | BCAT2FPR2HCAR2LMNAGAA | |
| SCHEMBL890126 | 0.81 | BCAT2 (0.36) | BCAT2FPR2HCAR2LRRK2TSHR | |
| SCHEMBL8907560 | 0.81 | BCAT2 (0.36) | BCAT2HCAR2LRRK2 | |
| SCHEMBL2160122 | 0.81 | ALDH1A1 (0.41) | BCAT2FPR2HCAR2LMNAGAA | |
| SCHEMBL2160129 | 0.81 | ALDH1A1 (0.41) | BCAT2FPR2HCAR2LMNAGAA | |
| SCHEMBL8921088 | 0.77 | MEN1 (0.37) | BCAT2HCAR2HPGDLRRK2 | |
| SCHEMBL8910369 | 0.77 | BCAT2 (0.37) | BCAT2HCAR2LMNAGAAHPGD | |
| SCHEMBL8185770 | 0.73 | NPR3 (0.49) | LMNA | |
| SCHEMBL12977805 | 0.72 | CCNA2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9765087-B2 | Benzimidazole derivatives | ENANTA PHARMACEUTICALS, INC. (US) | 2017-09-19 | — | — | US | disclosed |