Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.30 |
| ▸ | CDK2 | P24941 | 3/20 | 0.30 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.30 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917351 | 0.81 | RAB9A (0.48) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL2160129 | 0.81 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1BCAT2HCAR2 | |
| SCHEMBL890126 | 0.81 | BCAT2 (0.36) | ALDH1A1BCAT2HCAR2DYRK1ALRRK2 | |
| SCHEMBL8907560 | 0.81 | BCAT2 (0.36) | ALDH1A1BCAT2HCAR2DYRK1ALRRK2 | |
| SCHEMBL756357 | 0.81 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1BCAT2HCAR2 | |
| SCHEMBL2160122 | 0.81 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1BCAT2HCAR2 | |
| SCHEMBL19364698 | 0.77 | BCAT2 (0.33) | BCAT2HCAR2LRRK2HPGD | |
| SCHEMBL8910369 | 0.77 | BCAT2 (0.37) | MEN1KMT2ABCAT2NPC1RAB9A | |
| SCHEMBL8185770 | 0.73 | NPR3 (0.49) | KMT2A | |
| SCHEMBL12977805 | 0.72 | CCNA2 (0.31) | CCNA2CDK2CCNA1CDK5DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2400846-B1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARM INC (US) | 2016-10-05 | — | — | EP | disclosed |
| US-8188132-B2 | Linked dibenzimidazole derivatives | ENANTA PHARMACEUTICALS, INC. (US) | 2012-05-29 | — | — | US | disclosed |
| US-20100221214-A1 | LINKED DIBENZIMIDAZOLE DERIVATIVES | ENANTA PHARMACEUTICALS, INC. | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100221214-A1 | LINKED DIBENZIMIDAZOLE DERIVATIVES | EIF2AK2, NSUN2, ZC3HAV1 | MEN1 4801/4885KMT2A 2014/4885ALDH1A1 287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.