Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 6/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.34 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.34 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MPL | P40238 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19670569 | 0.89 | FAAH (0.36) | FAAHCYP11B2ABL1WNT3ARPS6KA2 | |
| SCHEMBL19364831 | 0.88 | CYP11B2 (0.41) | CYP11B2ABL1WNT3AFGFR4PORCN | |
| SCHEMBL19365531 | 0.87 | FGFR4 (0.49) | FAAHABL1WNT3AFGFR4RPS6KA2 | |
| SCHEMBL19365504 | 0.84 | CYP11B2 (0.37) | CYP11B2ABL1WNT3AFGFR4PORCN | |
| SCHEMBL19365719 | 0.83 | HTR2C (0.52) | — | |
| SCHEMBL12654199 | 0.83 | FGFR4 (0.44) | FAAHCYP11B2ABL1WNT3AFGFR4 | |
| SCHEMBL19365738 | 0.83 | FGFR4 (0.37) | CYP11B2ABL1WNT3AFGFR4PORCN | |
| SCHEMBL19365813 | 0.82 | RPS6KA3 (0.36) | CYP11B2ABL1WNT3ARPS6KA2 | |
| SCHEMBL20632688 | 0.81 | ABL1 (0.34) | CYP11B2ABL1WNT3AFGFR4GAA | |
| SCHEMBL19365819 | 0.81 | PIK3CA (0.42) | WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9765075-B2 | Substituted bridged urea analogs as sirtuin modulators | GLAXOSMITHKLINE LLC (US) | 2017-09-19 | — | — | US | disclosed |