Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 8/20 | 0.42 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 2/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | WNT1 | P04628 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19365473 | 0.89 | FGFR4 (0.39) | FGFR4PRKCAGSK3BMET | |
| SCHEMBL19669050 | 0.86 | TRPV1 (0.35) | FGFR4PRKCAGSK3BTRPV1WNT3A | |
| SCHEMBL16776100 | 0.85 | FGFR4 (0.42) | FGFR4PRKCAGSK3BTRPV1CSF1R | |
| SCHEMBL19365298 | 0.84 | FGFR4 (0.43) | FGFR4KDRWNT3ACNR1 | |
| SCHEMBL19365693 | 0.84 | TRPV1 (0.34) | TRPV1WNT1 | |
| SCHEMBL17618590 | 0.79 | TRPV1 (0.36) | FGFR4PRKCAGSK3BTRPV1WNT3A | |
| SCHEMBL19670160 | 0.77 | PRMT5 (0.42) | FGFR4 | |
| SCHEMBL20632110 | 0.77 | NPY5R (0.36) | FGFR4METWNT3AAHRNPY5R | |
| SCHEMBL19670234 | 0.76 | FGFR4 (0.35) | FGFR4CSF1RMETKDR | |
| SCHEMBL12654432 | 0.76 | FGFR4 (0.43) | FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9765075-B2 | Substituted bridged urea analogs as sirtuin modulators | GLAXOSMITHKLINE LLC (US) | 2017-09-19 | — | — | US | disclosed |