Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | WNT1 | P04628 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 13/20 | 0.33 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.33 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19670220 | 0.86 | ROCK2 (0.34) | TRPV1ROCK2TRPV3 | |
| SCHEMBL20633013 | 0.86 | HTR2C (0.38) | TRPV1ROCK2PRMT3 | |
| SCHEMBL19365462 | 0.84 | FGFR4 (0.42) | TRPV1WNT1 | |
| SCHEMBL19365473 | 0.83 | FGFR4 (0.39) | — | |
| SCHEMBL19670295 | 0.83 | HTR2C (0.39) | TRPV1 | |
| SCHEMBL17618592 | 0.80 | PIM2 (0.34) | TRPV1ROCK2 | |
| SCHEMBL19365298 | 0.79 | FGFR4 (0.43) | — | |
| SCHEMBL16776101 | 0.79 | WDR5 (0.33) | PRMT3 | |
| SCHEMBL17655361 | 0.76 | ROCK2 (0.36) | TRPV1ROCK2PRMT3 | |
| SCHEMBL19670379 | 0.76 | PRMT5 (0.37) | ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9765075-B2 | Substituted bridged urea analogs as sirtuin modulators | GLAXOSMITHKLINE LLC (US) | 2017-09-19 | — | — | US | disclosed |