Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 6/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 2/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | LGMN | Q99538 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19366988 | 0.91 | S1PR1 (0.36) | S1PR1KCNH2ALOX5APGRIN2BELANE | |
| SCHEMBL18926512 | 0.90 | S1PR1 (0.42) | S1PR1KCNH2ALOX5APELANE | |
| SCHEMBL19366898 | 0.90 | KCNH2 (0.43) | KCNH2PTGS2CA12CA1CA2 | |
| SCHEMBL19366990 | 0.87 | S1PR1 (0.36) | S1PR1KCNH2ALOX5APELANEPTGS2 | |
| SCHEMBL19366952 | 0.87 | CTSS (0.39) | S1PR1KCNH2GRIN2BELANEPTGS2 | |
| SCHEMBL17432172 | 0.87 | KCNH2 (0.45) | KCNH2PTGS2CA12CA1CA2 | |
| SCHEMBL18926510 | 0.87 | USP1 (0.35) | S1PR1KCNH2PTGS2LGMNCA12 | |
| SCHEMBL19366984 | 0.87 | MEN1 (0.40) | KCNH2PTGS2CA12CA1CA2 | |
| SCHEMBL18926499 | 0.87 | KCNH2 (0.38) | KCNH2GRIN2BPTGS2CA12CA1 | |
| SCHEMBL17432135 | 0.87 | RORC (0.39) | KCNH2ALOX5APGRIN2BPTGS2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9809587-B2 | Pesticidally active heterocyclic derivatives with sulphur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2017-11-07 | — | — | US | disclosed |
| US-9809587-B2 | Pesticidally active heterocyclic derivatives with sulphur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2017-11-07 | — | — | US | disclosed |
| US-20170267672-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-21 | — | — | US | disclosed |
| US-20170267672-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170267672-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | DDT, ACHE, GSTM1 | S1PR1 2522/4885KCNH2 1460/4885DGAT1 2371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.