SCHEMBL19367191

SCHEMBL19367191

CCC(C)(C)C(=O)C(=O)N1CCC[C@@H]1Cc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 12/20 0.62
GABRA1 P14867 1/20 0.52
GABRG2 P18507 1/20 0.52
GABRB3 P28472 1/20 0.52
GABRA3 P34903 1/20 0.52
GABRA2 P47869 1/20 0.52
GABRB2 P47870 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19367186 1.00 FKBP1A (0.62) FKBP1AGABRA1GABRG2GABRB3GABRA3
SCHEMBL18510347 1.00 FKBP1A (0.62) FKBP1AGABRA1GABRG2GABRB3GABRA3
SCHEMBL19372465 0.86 FKBP1A (0.66) FKBP1A
SCHEMBL5700640 0.82 FKBP1A (0.67) FKBP1A
SCHEMBL5700650 0.82 FKBP1A (0.66) FKBP1A
SCHEMBL7458418 0.81 FKBP1A (0.60) FKBP1A
SCHEMBL18510345 0.80 RIPK1 (0.65) FKBP1A
SCHEMBL14407876 0.79 FKBP1A (0.52) FKBP1A
SCHEMBL6098874 0.78 FKBP1A (0.71) FKBP1A
SCHEMBL6098871 0.78 FKBP1A (0.71) FKBP1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020191265-A1 METHODS FOR TREATING PULMONARY FIBROSIS DAVID WEINSTEIN CONSULTING, INC. (US) 2020-09-24 WO disclosed
US-10709686-B2 Methods for treating pulmonary fibrosis DAVID WEINSTEIN CONSULTING, INC. (US) 2020-07-14 US disclosed
US-20190290612-A1 METHODS FOR TREATING PULMONARY FIBROSIS DAVID WEINSTEIN CONSULTING INC (US) 2019-09-26 US disclosed
US-20180140576-A1 METHODS FOR WOUND HEALING AND SCAR PREVENTION DAVID WEINSTEIN CONSULTING INC (US) 2018-05-24 US disclosed
US-20180140576-A1 METHODS FOR WOUND HEALING AND SCAR PREVENTION DAVID WEINSTEIN CONSULTING INC (US) 2018-05-24 US disclosed
WO-2017165119-A1 METHODS FOR WOUND HEALING AND SCAR PREVENTION WEINSTEIN DAVID (US) 2017-09-28 WO disclosed
US-20170266157-A1 METHODS FOR WOUND HEALING AND SCAR PREVENTION DAVID WEINSTEIN CONSULTING, INC. 2017-09-21 US disclosed
US-20170266157-A1 METHODS FOR WOUND HEALING AND SCAR PREVENTION DAVID WEINSTEIN CONSULTING, INC. 2017-09-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10709686-B2 Methods for treating pulmonary fibrosis FKBP4, FKBP1B, FKBP3 FKBP1A 7/4885GABRA1 2619/4885GABRG2 2600/4885
US-20180140576-A1 METHODS FOR WOUND HEALING AND SCAR PREVENTION FKBP4, S100A4, FKBP14 FKBP1A 5/4885GABRA1 3278/4885GABRG2 3211/4885
US-20170266157-A1 METHODS FOR WOUND HEALING AND SCAR PREVENTION FKBP4, S100A4, FKBP14 FKBP1A 5/4885GABRA1 3278/4885GABRG2 3211/4885
US-20190290612-A1 METHODS FOR TREATING PULMONARY FIBROSIS FKBP4, FKBP1B, FKBP3 FKBP1A 7/4885GABRA1 2619/4885GABRG2 2600/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.