Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1937598 | 0.90 | PDK2 (0.36) | PDK2CA1CA2 | |
| SCHEMBL871382 | 0.89 | PDK2 (0.36) | TYMSPDK2CA1CA2ORAI1 | |
| SCHEMBL21863425 | 0.89 | PDK2 (0.36) | TYMSPDK2CA1CA2ORAI1 | |
| SCHEMBL1936965 | 0.86 | FABP4 (0.34) | TYMSPDK2CA1CA2ORAI1 | |
| SCHEMBL12173998 | 0.85 | — | — | |
| SCHEMBL870417 | 0.83 | PDK2 (0.34) | PDK2CA1CA2ORAI1 | |
| SCHEMBL2780339 | 0.82 | ACLY (0.38) | PDK2ORAI1 | |
| SCHEMBL13458407 | 0.82 | PDK2 (0.33) | PDK2ORAI1 | |
| SCHEMBL30313890 | 0.82 | ACLY (0.38) | PDK2ORAI1 | |
| SCHEMBL27964299 | 0.82 | HPGD (0.35) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9282742-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2016-03-15 | — | — | US | disclosed |
| US-9282742-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2016-03-15 | — | — | US | disclosed |
| US-9216973-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2015-12-22 | — | — | US | disclosed |
| US-9216973-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2015-12-22 | — | — | US | disclosed |
| US-9216973-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2015-12-22 | — | — | US | disclosed |
| EP-2331535-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-07-22 | — | — | EP | disclosed |
| EP-2331535-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-07-22 | — | — | EP | disclosed |
| US-20140350061-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2014-11-27 | — | — | US | disclosed |
| US-20140350061-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2014-11-27 | — | — | US | disclosed |
| US-20140350061-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2014-11-27 | — | — | US | disclosed |
| US-20110269804-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2011-11-03 | — | — | US | disclosed |
| US-20110166193-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2011-07-07 | — | — | US | disclosed |
| US-20110166193-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2011-07-07 | — | — | US | disclosed |
| US-20110166193-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2011-07-07 | — | — | US | disclosed |
| EP-2331535-A1 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2011-06-15 | — | — | EP | disclosed |
| EP-2331536-A1 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010025998-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-03-11 | — | — | WO | disclosed |
| WO-2010025998-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-03-11 | — | — | WO | disclosed |
| WO-2010020522-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-02-25 | — | — | WO | disclosed |
| WO-2010020522-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140350061-A1 | INSECTICIDAL COMPOUNDS | CHRM1, ACHE, CHRM2 | TYMS 4252/4885PDK2 4141/4885CA1 631/4885 |
| US-20110166193-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, MSL1 | TYMS 4066/4885PDK2 3788/4885CA1 1048/4885 |
| US-20110269804-A1 | INSECTICIDAL COMPOUNDS | CHRM1, CHRM2, C1R | TYMS 4540/4885PDK2 4816/4885CA1 1254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.