Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 4/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 8/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30301334 | 0.84 | HSD11B1 (0.51) | HSD11B1LMNASMN1; SMN2STSCA12 | |
| SCHEMBL1938706 | 0.84 | HSD11B1 (0.51) | HSD11B1LMNASMN1; SMN2STSCA12 | |
| SCHEMBL1937493 | 0.81 | HSD17B10 (0.51) | XDHLMNAMAPK1HTTALDH1A1 | |
| SCHEMBL1937101 | 0.80 | HSD17B10 (0.53) | XDHLMNAALDH1A1 | |
| SCHEMBL32677438 | 0.80 | HSD17B10 (0.53) | XDHLMNAALDH1A1 | |
| SCHEMBL17099790 | 0.79 | LMNA (0.48) | HSD11B1LMNASMN1; SMN2MAPK1HTT | |
| SCHEMBL30480094 | 0.79 | LMNA (0.48) | HSD11B1LMNASMN1; SMN2MAPK1HTT | |
| SCHEMBL10054976 | 0.78 | MAOA (0.61) | XDHHSD11B1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL25107807 | 0.77 | HSD17B10 (0.49) | XDHSMN1; SMN2ALDH1A1 | |
| SCHEMBL12268389 | 0.77 | HSD11B1 (0.48) | HSD11B1LMNASMN1; SMN2STSCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110212955-A1 | ROSAMINE DERIVATIVES AS AGENTS FOR THE TREATMENT OF CANCER | CANCER RESEARCH INITIATIVES FOUNDATION (MY) | 2011-09-01 | — | — | US | disclosed |
| EP-2331520-A1 | ROSAMINE DERIVATIVES AS AGENTS FOR THE TREATMENT OF CANCER | Cancer Research Initiative Foundation (MY) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010033011-A1 | ROSAMINE DERIVATIVES AS AGENTS FOR THE TREATMENT OF CANCER | CANCER RESEARCH INITIATIVES FOUNDATION (MY) | 2010-03-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212955-A1 | ROSAMINE DERIVATIVES AS AGENTS FOR THE TREATMENT OF CANCER | LTB4R, LTB4R2, NR1H3 | XDH 997/4885HSD11B1 336/4885LMNA 2105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.