Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 5/20 | 0.41 |
| ▸ | TRPC5 | Q9UL62 | 11/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18834584 | 0.75 | TRPC5 (0.50) | TRPC5TP53ADRA2AKCNH2TRPC4 | |
| SCHEMBL18834573 | 0.72 | TRPC5 (0.51) | TRPC5TP53ADRA2AKCNH2TRPC4 | |
| SCHEMBL16076129 | 0.67 | P2RX3 (0.56) | P2RX3TRPC5KCNH2TRPC4 | |
| SCHEMBL19375348 | 0.67 | TRPC5 (0.47) | TRPC5 | |
| SCHEMBL18834990 | 0.65 | ALDH1A1 (0.48) | P2RX3TRPC5TP53KCNH2TRPC4 | |
| SCHEMBL16076121 | 0.65 | TRPC5 (0.54) | P2RX3TRPC5TP53KCNH2TRPC4 | |
| SCHEMBL19374943 | 0.64 | TRPC5 (0.40) | TRPC5TP53ADRA2AKCNH2TRPC4 | |
| SCHEMBL16076263 | 0.64 | TRPC5 (0.53) | P2RX3TRPC5TP53KCNH2TRPC4 | |
| SCHEMBL16028059 | 0.62 | TRPC5 (0.54) | P2RX3TRPC5TP53KCNH2TRPC4 | |
| SCHEMBL19375583 | 0.62 | MAPT (0.37) | TRPC5TP53ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B9 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-09-20 | — | — | EP | disclosed |