Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | BPTF | Q12830 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.35 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10839015 | 0.73 | OPRK1 (0.38) | CYP19A1BPTFGRM2GRM3ABHD6 | |
| SCHEMBL7058755 | 0.72 | DDB1 (0.42) | — | |
| SCHEMBL4916128 | 0.67 | ADRA1D (0.47) | SIGMAR1 | |
| SCHEMBL8176747 | 0.67 | SMN1; SMN2 (0.39) | MAOAMAOBCYP19A1PARP1GRM2 | |
| SCHEMBL14292546 | 0.67 | BPTF (0.39) | MAOAMAOBSIGMAR1CYP19A1BPTF | |
| SCHEMBL7039965 | 0.66 | CHRNB2 (0.56) | MAOAMAOBSIGMAR1CYP19A1CYP11B1 | |
| SCHEMBL1066829 | 0.66 | MAOB (0.50) | MAOAMAOBSIGMAR1CYP19A1 | |
| SCHEMBL15066985 | 0.64 | GLA (0.34) | — | |
| SCHEMBL10557142 | 0.64 | SIGMAR1 (0.56) | MAOAMAOBSIGMAR1CYP19A1 | |
| SCHEMBL2154372 | 0.64 | MAOB (0.86) | MAOAMAOBSIGMAR1CYP19A1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2330904-A2 | 4-ALKYL-SUBSTITUTED DIAMINOPYRIMIDINES | Bayer CropScience AG (DE) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010025863-A2 | 4-ALKYL-SUBSTITUTED DIAMINOPYRIMIDINES | BAYER CROPSCIENCE AG (DE) | 2010-03-11 | — | — | WO | disclosed |