Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15303513 | 0.85 | MTNR1A (0.35) | MTNR1AMTNR1B | |
| SCHEMBL21116386 | 0.85 | MTNR1A (0.35) | MTNR1AMTNR1B | |
| SCHEMBL15303511 | 0.85 | MTNR1A (0.35) | MTNR1AMTNR1B | |
| SCHEMBL15303706 | 0.84 | MTNR1A (0.34) | MTNR1AMTNR1B | |
| SCHEMBL15303300 | 0.83 | MTNR1A (0.33) | MTNR1AMTNR1BTSHR | |
| SCHEMBL21116581 | 0.81 | MTNR1A (0.33) | MTNR1AMTNR1B | |
| SCHEMBL15306236 | 0.81 | MTNR1A (0.33) | MTNR1AMTNR1B | |
| SCHEMBL19400272 | 0.79 | ALDH1A1 (0.39) | MTNR1AMTNR1B | |
| SCHEMBL9900479 | 0.73 | RAB9A (0.36) | MTNR1AMTNR1B | |
| SCHEMBL17188929 | 0.72 | GABRA5 (0.35) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170273981-A1 | HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS | GLAXOSMITHKLINE S.P.A. (IT) | 2017-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170273981-A1 | HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS | KCNA3, KCND3, KCNN3 | MTNR1A 2602/4885MTNR1B 2698/4885TSHR 4243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.