Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | CD69 | Q07108 | 4/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL902241 | 0.78 | ALOX15 (0.53) | KMT2ACD69ALOX15ALDH1A1KDM4E | |
| SCHEMBL1619453 | 0.75 | ALOX15 (0.41) | KMT2ACD69ALOX15KDM4ELMNA | |
| SCHEMBL1145948 | 0.74 | KMT2A (0.62) | KMT2ACD69ALOX15ALDH1A1KDM4E | |
| SCHEMBL9646424 | 0.72 | KMT2A (0.66) | KMT2ACD69ALOX15ALDH1A1KDM4E | |
| SCHEMBL22191169 | 0.72 | KMT2A (0.60) | KMT2ACD69ALOX15ALDH1A1KDM4E | |
| SCHEMBL830740 | 0.72 | KMT2A (0.60) | KMT2ACD69ALOX15ALDH1A1KDM4E | |
| SCHEMBL20509584 | 0.72 | KMT2A (0.60) | KMT2ACD69ALOX15ALDH1A1KDM4E | |
| SCHEMBL6743196 | 0.72 | KMT2A (0.60) | KMT2ACD69ALOX15ALDH1A1KDM4E | |
| SCHEMBL3729436 | 0.72 | KMT2A (1.00) | KMT2ACD69ALOX15ALDH1A1KDM4E | |
| SCHEMBL2059516 | 0.72 | KMT2A (0.55) | KMT2ACD69ALOX15ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110212955-A1 | ROSAMINE DERIVATIVES AS AGENTS FOR THE TREATMENT OF CANCER | CANCER RESEARCH INITIATIVES FOUNDATION (MY) | 2011-09-01 | — | — | US | disclosed |
| EP-2331520-A1 | ROSAMINE DERIVATIVES AS AGENTS FOR THE TREATMENT OF CANCER | Cancer Research Initiative Foundation (MY) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010033011-A1 | ROSAMINE DERIVATIVES AS AGENTS FOR THE TREATMENT OF CANCER | CANCER RESEARCH INITIATIVES FOUNDATION (MY) | 2010-03-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212955-A1 | ROSAMINE DERIVATIVES AS AGENTS FOR THE TREATMENT OF CANCER | LTB4R, LTB4R2, NR1H3 | KMT2A 2654/4885CD69 1960/4885ALOX15 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.