Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | GLP1R | P43220 | 10/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | SMO | Q99835 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19400676 | 1.00 | L3MBTL1 (0.36) | L3MBTL1CHRM3GLP1RCYP3A4CYP2D6 | |
| SCHEMBL14193971 | 0.81 | CHRM3 (0.36) | L3MBTL1CHRM3GLP1RCYP3A4CYP2D6 | |
| SCHEMBL2000106 | 0.81 | CHRM3 (0.36) | L3MBTL1CHRM3GLP1RCYP3A4CYP2D6 | |
| SCHEMBL27323692 | 0.81 | CHRM3 (0.36) | L3MBTL1CHRM3GLP1RCYP3A4CYP2D6 | |
| SCHEMBL58010 | 0.78 | CHRM3 (0.35) | L3MBTL1CHRM3HTT | |
| SCHEMBL463540 | 0.78 | CHRM3 (0.35) | L3MBTL1CHRM3HTT | |
| SCHEMBL11997996 | 0.78 | CHRM3 (0.35) | L3MBTL1CHRM3HTT | |
| SCHEMBL14509706 | 0.76 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL26997769 | 0.76 | CHRM3 (0.37) | L3MBTL1CHRM3GLP1RCYP3A4CYP2D6 | |
| SCHEMBL26209173 | 0.76 | ITGB3 (0.41) | L3MBTL1CHRM3GLP1RCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170275249-A1 | SMALL LIPOPEPTIDOMIMETIC INHIBITORS OF GHRELIN O-ACYL TRANSFERASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170275249-A1 | SMALL LIPOPEPTIDOMIMETIC INHIBITORS OF GHRELIN O-ACYL TRANSFERASE | LIPE, MBOAT4, GHSR | L3MBTL1 243/4885CHRM3 3857/4885GLP1R 80/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.