SCHEMBL194033

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL193844	0.90	KDM4E (0.39)	KDM4EHSD17B10ALDH1A1NPC1LMNA
	SCHEMBL13182042	0.82	PTGES (0.43)	KDM4EHSD17B10ALDH1A1SMN1; SMN2MEN1
	SCHEMBL15986292	0.78	ALDH1A1 (0.47)	KDM4EALDH1A1NPC1LMNARAB9A
	SCHEMBL15936022	0.75	KMT2A (0.42)	KDM4EHSD17B10ALDH1A1POLBRECQL
	SCHEMBL28221563	0.75	GSK3B (0.53)	HSD17B10NPC1HPGDRAB9AMEN1
	SCHEMBL193885	0.73	KDM4E (0.39)	KDM4EHSD17B10ALDH1A1LMNAHPGD
	SCHEMBL194128	0.69	AXL (0.45)	KDM4EHSD17B10ALDH1A1SMN1; SMN2KMT2A
	SCHEMBL194725	0.68	ALDH1A1 (0.54)	KDM4EHSD17B10ALDH1A1SMN1; SMN2POLB
	SCHEMBL194908	0.66	KDM4E (0.42)	KDM4EHSD17B10ALDH1A1SMN1; SMN2POLB
	SCHEMBL11154998	0.66	GSK3B (0.48)	HSD17B10ALDH1A1SMN1; SMN2POLBRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.