SCHEMBL194128

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13182042	0.84	PTGES (0.43)	KDM4EALDH1A1KMT2AGAAMAPT
	SCHEMBL194725	0.83	ALDH1A1 (0.54)	KDM4EALDH1A1KMT2AGAAMAPT
	SCHEMBL193844	0.81	KDM4E (0.39)	AXLKEAP1KDM4EALDH1A1KMT2A
	SCHEMBL29816254	0.77	HSD17B10 (0.45)	KDM4EALDH1A1KMT2AMAPTHSD17B10
	SCHEMBL15996314	0.75	AR (0.48)	KDM4EALDH1A1KMT2AGAAMAPT
	SCHEMBL194942	0.74	PTGS2 (0.47)	KDM4EALDH1A1KMT2AGAAMAPT
	SCHEMBL194615	0.73	ALDH1A1 (0.48)	KDM4EALDH1A1KMT2AGAAMAPT
	SCHEMBL10278516	0.72	AR (0.43)	KDM4EALDH1A1KMT2AGAAHSD17B10
	SCHEMBL29816169	0.72	GAA (0.60)	KDM4EALDH1A1GAAMAPTHTT
	SCHEMBL28814141	0.72	KDM4E (0.48)	KDM4EALDH1A1KMT2AGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.