Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | GBA1 | P04062 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23369518 | 0.79 | LMNA (0.37) | ALDH1A1LMNARAB9ANPC1HTT | |
| SCHEMBL17992227 | 0.78 | ALDH1A1 (0.51) | ALDH1A1LMNARAB9AKDM4ENPC1 | |
| SCHEMBL17224134 | 0.72 | GSK3B (0.45) | ALDH1A1RAB9AKDM4ETSHR | |
| SCHEMBL19404643 | 0.71 | PKM (0.37) | ALDH1A1RAB9AKDM4ENPC1HSD17B10 | |
| SCHEMBL1403879 | 0.68 | ALDH1A1 (0.40) | ALDH1A1RAB9AKDM4ENPC1HSD17B10 | |
| SCHEMBL17697619 | 0.67 | SMN1; SMN2 (0.43) | ALDH1A1RAB9AKDM4ENPC1TSHR | |
| SCHEMBL15260359 | 0.67 | HTT (0.44) | ALDH1A1RAB9AKDM4ENPC1TSHR | |
| SCHEMBL5011310 | 0.67 | HCRTR1 (0.44) | ALDH1A1LMNARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL21778743 | 0.66 | SIRT6 (0.49) | ALDH1A1LMNARAB9AKDM4ENPC1 | |
| SCHEMBL1721213 | 0.66 | GBA1 (0.38) | ALDH1A1RAB9AKDM4ENPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017164108-A1 | HETEROCYCLIC COMPOUND | 住友化学株式会社 | 2017-09-28 | — | — | WO | disclosed |