Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | NOS3 | P29474 | 2/20 | 0.42 |
| ▸ | NOS1 | P29475 | 2/20 | 0.42 |
| ▸ | NOS2 | P35228 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ABAT | P80404 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28670034 | 0.82 | MAPT (0.71) | THRATHRBMAPTSMN1; SMN2KMT2A | |
| SCHEMBL11839721 | 0.82 | LOXL2 (0.58) | THRATHRBLOXL2MAPTSMN1; SMN2 | |
| SCHEMBL9850596 | 0.82 | THRA (0.64) | THRATHRBMAPTSMN1; SMN2KMT2A | |
| SCHEMBL21840691 | 0.82 | THRA (0.59) | THRATHRBMAPTSMN1; SMN2NOS3 | |
| SCHEMBL18286692 | 0.80 | THRB (0.57) | THRATHRBMAPTHDAC6KMT2A | |
| Ethylene SCHEMBL11090983 | 0.79 | KMT2A (0.61) | LOXL2MAPTHDAC3HDAC6NCOR2 | |
| SCHEMBL7493555 | 0.79 | HDAC3 (0.57) | LOXL2HDAC3HDAC6NCOR2KDM4E | |
| SCHEMBL2399333 | 0.79 | LOXL2 (0.52) | LOXL2HDAC3HDAC6NCOR2KDM4E | |
| SCHEMBL856509 | 0.79 | KMT2A (0.67) | LOXL2MAPTHDAC3HDAC6NCOR2 | |
| SCHEMBL11645482 | 0.78 | THRB (0.75) | THRATHRBMAPTKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017163264-A1 | BLOCKING TOLL-LIKE RECEPTOR 9 SIGNALING WITH SMALL MOLECULE ANTAGONIST | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-09-28 | — | — | WO | disclosed |