Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 8/20 | 0.75 |
| ▸ | THRA | P10827 | 6/20 | 0.75 |
| ▸ | PLK1 | P53350 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 1/20 | 0.43 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850596 | 0.84 | THRA (0.64) | THRBTHRAPLK1MAPTPOLB | |
| SCHEMBL11047142 | 0.82 | THRB (0.63) | THRBTHRAPLK1MAPTL3MBTL1 | |
| SCHEMBL28670034 | 0.81 | MAPT (0.71) | THRBTHRAMAPTKMT2AMEN1 | |
| SCHEMBL21840691 | 0.80 | THRA (0.59) | THRBTHRAMAPTALDH1A1KMT2A | |
| SCHEMBL29062361 | 0.80 | L3MBTL1 (0.59) | THRBTHRAPLK1MAPTL3MBTL1 | |
| SCHEMBL1363306 | 0.79 | THRB (0.55) | THRBTHRAPLK1MAPTL3MBTL1 | |
| SCHEMBL1483217 | 0.79 | KMT2A (0.64) | THRBTHRAPLK1MAPTL3MBTL1 | |
| SCHEMBL18286692 | 0.78 | THRB (0.57) | THRBTHRAPLK1MAPTALDH1A1 | |
| SCHEMBL19405232 | 0.78 | THRA (0.57) | THRBTHRAMAPTKDM4EKMT2A | |
| SCHEMBL2830327 | 0.78 | CES2 (0.60) | THRBPLK1L3MBTL1POLBCTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4104333-A | COMPOSITIONS CONTAINING CROSSLINKING MONOMERS, MONOACRYLATES, INITIATORS AND ACCELERATORS | LEE PHARMACEUTICALS (US) | 1978-08-01 | — | — | US | disclosed |