Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | PLK1 | P53350 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6259079 | 0.84 | ALDH1A1 (0.70) | ALDH1A1MAPTPLK1SMN1; SMN2TDP1 | |
| SCHEMBL28670034 | 0.84 | MAPT (0.71) | THRATHRBMAPTSMN1; SMN2KMT2A | |
| SCHEMBL11645482 | 0.84 | THRB (0.75) | THRATHRBALDH1A1MAPTPLK1 | |
| SCHEMBL21840691 | 0.83 | THRA (0.59) | THRATHRBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL17802303 | 0.83 | ALDH1A1 (0.61) | THRATHRBALDH1A1MAPTPLK1 | |
| SCHEMBL19405232 | 0.82 | THRA (0.57) | THRATHRBMAPTSMN1; SMN2KMT2A | |
| SCHEMBL18286692 | 0.82 | THRB (0.57) | THRATHRBALDH1A1MAPTPLK1 | |
| SCHEMBL4211721 | 0.80 | ALDH1A1 (0.64) | THRBALDH1A1MAPTPLK1SMN1; SMN2 | |
| SCHEMBL14291711 | 0.79 | ALDH1A1 (0.57) | THRATHRBALDH1A1MAPTPLK1 | |
| SCHEMBL28404667 | 0.78 | ALDH1A1 (0.68) | ALDH1A1PLK1SMN1; SMN2TDP1TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-54066640-A | — | — | None | — | — | JP | disclosed |
| EP-0423524-A2 | Propiophenone derivatives and their preparation and pharmaceutical use | MARUHO Co., Ltd. (JP) | 1991-04-24 | — | — | EP | disclosed |
| JP-S5466640-A | NOVEL ACRYLOPHENONE DERIVATIVE AND ITS PREPARATION | ASAHI CHEM IND CO LTD | 1979-05-29 | — | — | JP | disclosed |