Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 2/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.30 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19743756 | 0.82 | MBOAT4 (0.32) | KDM4EUSP2HPGDHSD17B10NOS3 | |
| SCHEMBL3055813 | 0.75 | ALDH1A1 (0.39) | ALDH1A1MAPTNOS3NOS1NOS2 | |
| SCHEMBL2629371 | 0.75 | APLNR (0.41) | KDM4EUSP2HPGDHSD17B10NOS3 | |
| SCHEMBL19979074 | 0.73 | NOS3 (0.39) | KDM4EALDH1A1MAPTNOS3NOS1 | |
| SCHEMBL27994328 | 0.73 | ALDH1A1 (0.38) | ALDH1A1MAPTNOS3NOS1NOS2 | |
| SCHEMBL12890891 | 0.72 | LMNA (0.33) | KDM4EUSP2HPGDHSD17B10NOS3 | |
| SCHEMBL20313916 | 0.72 | NOS3 (0.33) | KDM4EUSP2HPGDHSD17B10NOS3 | |
| SCHEMBL19743808 | 0.71 | AAK1 (0.31) | — | |
| SCHEMBL22275388 | 0.71 | S1PR1 (0.39) | KDM4EALDH1A1MAPT | |
| SCHEMBL21480933 | 0.71 | ALDH1A1 (0.40) | KDM4EUSP2HPGDHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9780310-B2 | Heterocyclic compound for organic electroluminescent device and its application | TOSOH CORPORATION (JP) | 2017-10-03 | — | — | US | disclosed |