Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 8/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18560515 | 0.88 | KDM2B (0.43) | KDM2BNPC1RAB9AHSD11B1POLB | |
| SCHEMBL18569336 | 0.79 | TSHR (0.46) | NPC1RAB9AALDH1A1MAPK1POLB | |
| SCHEMBL18560516 | 0.75 | ALDH1A1 (0.42) | ALDH1A1KMT2A | |
| SCHEMBL17949736 | 0.74 | NPC1 (0.60) | KDM2BNPC1RAB9AALDH1A1HSD11B1 | |
| SCHEMBL3367257 | 0.72 | NPC1 (0.77) | KDM2BNPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL19415101 | 0.70 | THRA (0.41) | KDM2BNPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL27957268 | 0.70 | HSD11B1 (0.61) | KDM2BNPC1RAB9AALDH1A1HSD11B1 | |
| SCHEMBL20627946 | 0.69 | MAPT (0.46) | RAB9AALDH1A1MAPK1POLBKMT2A | |
| SCHEMBL9136904 | 0.69 | NPC1 (0.77) | KDM2BNPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL26424729 | 0.69 | MEN1 (0.68) | NPC1RAB9AALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3225631-A1 | DOUBLE-ACYLATED GLP-1 DERIVATIVES | NOVO NORDISK A/S (DK) | 2017-10-04 | — | — | EP | disclosed |