Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | NMT1 | P30419 | 4/20 | 0.40 |
| ▸ | NMT2 | O60551 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19416398 | 0.87 | TLR8 (0.41) | CREBBPALOX5ADAM17MMP1 | |
| SCHEMBL19265484 | 0.81 | PPARG (0.41) | HSP90AA1CREBBPPPARGALDH1A1MAPT | |
| SCHEMBL19265526 | 0.79 | TLR8 (0.40) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL18771963 | 0.77 | MMP2 (0.41) | ALOX5ALDH1A1HPGD | |
| SCHEMBL18771974 | 0.76 | MMP2 (0.45) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL18771997 | 0.76 | TLR8 (0.45) | KMT2AALDH1A1MAPTHPGDLMNA | |
| SCHEMBL18771933 | 0.76 | TLR8 (0.34) | ALDH1A1MAPTHPGD | |
| SCHEMBL18772024 | 0.76 | TLR8 (0.56) | CREBBPALDH1A1MAPT | |
| SCHEMBL18772002 | 0.75 | HPGD (0.37) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL19265638 | 0.75 | KDM4E (0.36) | ALOX5ALDH1A1ESR1JAK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3225623-A1 | SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | Ventirx Pharmaceuticals, Inc. (US) | 2017-10-04 | — | — | EP | disclosed |