Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19416546 | 0.81 | MEN1 (0.41) | PPARGCREBBPALDH1A1HPGDMAPT | |
| SCHEMBL19265526 | 0.80 | TLR8 (0.40) | NPC1RAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL18772117 | 0.79 | KDM4E (0.39) | NPC1RAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL19265644 | 0.78 | MMP2 (0.41) | ALDH1A1HPGDSMN1; SMN2CASP1HSD17B10 | |
| SCHEMBL19265638 | 0.78 | KDM4E (0.36) | ALDH1A1TSHRSMN1; SMN2KDM4E | |
| SCHEMBL19265647 | 0.78 | PRKCZ (0.37) | ALDH1A1 | |
| SCHEMBL19265705 | 0.76 | FDFT1 (0.38) | RAB9AALDH1A1HPGDSMN1; SMN2MAOA | |
| SCHEMBL19265650 | 0.76 | KDM4E (0.39) | NPC1MAPK1RAB9AALDH1A1HPGD | |
| SCHEMBL19265541 | 0.75 | PPARA (0.33) | PPARGMAPK1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL10343251 | 0.73 | TLR8 (0.49) | PPARGPARP10NPC1MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3207930-A1 | SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | VentiRx Pharmaceuticals, Inc. (US) | 2017-08-23 | — | — | EP | disclosed |