Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 1/20 | 0.44 |
| ▸ | ICMT | O60725 | 6/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19406166 | 0.94 | PLA2G2A (0.47) | TSPOICMTPLA2G2AMAOAMAOB | |
| SCHEMBL19418007 | 0.92 | PLA2G2A (0.46) | PLA2G2AMAOAMAOBGRIN1GRIN2A | |
| SCHEMBL14261695 | 0.87 | ICMT (0.48) | TSPOICMTPLA2G2AMAOAMAOB | |
| SCHEMBL14261696 | 0.87 | ICMT (0.48) | TSPOICMTPLA2G2AMAOAMAOB | |
| SCHEMBL19418008 | 0.86 | GRIK2 (0.50) | TSPOKDM4EDYRK1A | |
| SCHEMBL19406164 | 0.84 | MAOA (0.58) | PLA2G2AMAOAMAOBGRIN1GRIN2A | |
| SCHEMBL3358616 | 0.81 | KDM4E (0.52) | TSPOPLA2G2AMAOAMAOBGRIN1 | |
| SCHEMBL17485888 | 0.80 | MAOA (0.56) | TSPOPLA2G2AMAOAMAOBGRIN1 | |
| SCHEMBL17485896 | 0.80 | MAOA (0.56) | TSPOPLA2G2AMAOAMAOBGRIN1 | |
| SCHEMBL19170247 | 0.80 | MAOA (0.56) | TSPOPLA2G2AMAOAMAOBGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3225624-A1 | NOVEL COMPOUND AND USE THEREOF AS A HOLE-TRANSPORT MATERIAL | Abengoa Research, S.L. (ES) | 2017-10-04 | — | — | EP | disclosed |