SCHEMBL3358616

SCHEMBL3358616

CCCCn1c2ccc(-c3ccc(OC)cc3)cc2c2cc(-c3ccc(OC)cc3)ccc21

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.52
HSD17B10 Q99714 1/20 0.52
TSPO P30536 3/20 0.51
MAOA P21397 2/20 0.50
MAOB P27338 2/20 0.50
GRIK2 Q13002 2/20 0.49
GRIK1 P39086 1/20 0.49
GRIN1 Q05586 1/20 0.48
GRIN2A Q12879 1/20 0.48
GRIN2B Q13224 1/20 0.48
PGR P06401 3/20 0.46
RORA P35398 2/20 0.46
RORC P51449 2/20 0.46
RORB Q92753 2/20 0.46
CNR1 P21554 1/20 0.46
CNR2 P34972 1/20 0.46
DYRK1A Q13627 1/20 0.45
PLA2G2A P14555 2/20 0.44
PTGER4 P35408 1/20 0.43
NPC1 O15118 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14160802 0.92 KDM4E (0.51) KDM4EHSD17B10TSPOMAOAMAOB
SCHEMBL19406166 0.86 PLA2G2A (0.47) KDM4EHSD17B10TSPOMAOAMAOB
SCHEMBL3365852 0.84 GRIK2 (0.61) KDM4ETSPOGRIK2GRIK1PTGER4
SCHEMBL13304800 0.83 TSHR (0.51) TSPOPGRRORARORCRORB
SCHEMBL14261696 0.82 ICMT (0.48) KDM4EHSD17B10TSPOMAOAMAOB
SCHEMBL14261695 0.82 ICMT (0.48) KDM4EHSD17B10TSPOMAOAMAOB
SCHEMBL19418005 0.81 TSPO (0.44) KDM4EHSD17B10TSPOMAOAMAOB
SCHEMBL13495964 0.81 ESR1 (0.52) KDM4EHSD17B10PGRRORARORC
SCHEMBL22042200 0.81 MAOA (0.68) KDM4EHSD17B10MAOAMAOBGRIN1
SCHEMBL22087155 0.81 MAOA (0.68) KDM4EHSD17B10MAOAMAOBGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100026168-A1 Hole Transport Material NATIONAL TAIWAN UNIVERSITY (TW) 2010-02-04 US disclosed