Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | TSPO | P30536 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 6/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 6/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 6/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 6/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 6/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | ICMT | O60725 | 2/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19418005 | 0.94 | TSPO (0.44) | PLA2G2AMAOAMAOBTSPOGRIN1 | |
| SCHEMBL19406164 | 0.89 | MAOA (0.58) | PLA2G2AMAOAMAOBGRIN1GRIN2A | |
| SCHEMBL3358616 | 0.86 | KDM4E (0.52) | PLA2G2AMAOAMAOBTSPOGRIN1 | |
| SCHEMBL19418007 | 0.85 | PLA2G2A (0.46) | PLA2G2AMAOAMAOBGRIN1GRIN2A | |
| SCHEMBL13592789 | 0.82 | ICMT (0.44) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL14160802 | 0.82 | KDM4E (0.51) | PLA2G2AMAOAMAOBTSPOGRIN1 | |
| SCHEMBL20994178 | 0.81 | ICMT (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL22042200 | 0.81 | MAOA (0.68) | PLA2G2AMAOAMAOBGRIN1GRIN2A | |
| SCHEMBL22087155 | 0.81 | MAOA (0.68) | PLA2G2AMAOAMAOBGRIN1GRIN2A | |
| SCHEMBL14261695 | 0.80 | ICMT (0.48) | PLA2G2AMAOAMAOBTSPOGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180006241-A1 | NOVEL COMPOUND AND USE THEREOF AS A HOLE TRANSPORT MATERIAL | ABENGOA RESEARCH, S.L. (ES) | 2018-01-04 | — | — | US | disclosed |
| EP-3225624-A1 | NOVEL COMPOUND AND USE THEREOF AS A HOLE-TRANSPORT MATERIAL | Abengoa Research, S.L. (ES) | 2017-10-04 | — | — | EP | disclosed |
| EP-3225624-A1 | NOVEL COMPOUND AND USE THEREOF AS A HOLE-TRANSPORT MATERIAL | Abengoa Research, S.L. (ES) | 2017-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180006241-A1 | NOVEL COMPOUND AND USE THEREOF AS A HOLE TRANSPORT MATERIAL | MITF, SLC39A11, TRPA1 | PLA2G2A 4184/4885MAOA 1204/4885MAOB 1343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.