Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1472949 | 0.80 | GABRA1 (0.46) | GABRA1GABRB2TAAR1CA12CA1 | |
| SCHEMBL1473762 | 0.74 | GABRA1 (0.36) | GABRA1GABRB2TAAR1CA12CA1 | |
| SCHEMBL759007 | 0.72 | CA12 (0.41) | GABRA1GABRB2TAAR1CA12CA1 | |
| SCHEMBL18608282 | 0.72 | ENPP2 (0.33) | ESR1ESR2AR | |
| SCHEMBL14189235 | 0.69 | CYP3A4 (0.47) | GABRA1GABRB2CA1BACE1ESR1 | |
| SCHEMBL16193055 | 0.68 | CYP3A4 (0.39) | GABRA1GABRB2TAAR1CA12CA1 | |
| SCHEMBL13176669 | 0.67 | ALOX15 (0.33) | GABRA1GABRB2CA1ESR1ESR2 | |
| Ethane SCHEMBL27965993 | 0.66 | CA1 (0.45) | GABRA1GABRB2TAAR1CA12CA1 | |
| SCHEMBL903958 | 0.66 | CA9 (0.45) | TAAR1CA12CA1CA9BACE1 | |
| SCHEMBL881046 | 0.66 | ALDH1A1 (0.45) | GABRA1GABRB2TAAR1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2820066-B1 | POLY (PHENYLENE ETHER) PROCESS | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2017-10-04 | — | — | EP | disclosed |