SCHEMBL19421

SCHEMBL19421

CC1(C)C2CCC1(C=C(O)c1ccccc1)C(=O)C2

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.41
KMT2A Q03164 5/20 0.41
ALDH1A1 P00352 2/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
CYP2C19 P33261 3/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
KDM4E B2RXH2 1/20 0.34
SMN1; SMN2 Q16637 3/20 0.33
NPSR1 Q6W5P4 2/20 0.33
TSHR P16473 1/20 0.33
HSD17B10 Q99714 1/20 0.33
HSP90AA1 P07900 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL150729 0.88 MEN1 (0.41) MEN1KMT2AALDH1A1LMNAMAPT
SCHEMBL1768748 0.84 CYP1A2 (0.40) MEN1KMT2AALDH1A1LMNAMAPT
SCHEMBL2903789 0.83 CYP1A2 (0.42) MEN1KMT2AALDH1A1LMNAMAPT
SCHEMBL6553778 0.80 CYP1A2 (0.42) MEN1KMT2AALDH1A1LMNAMAPT
SCHEMBL20455791 0.77 KMT2A (0.44) MEN1KMT2AALDH1A1LMNAMAPT
SCHEMBL345420 0.75 TRPM8 (0.37) ALDH1A1LMNACYP2C19CYP1A2
Methylamine SCHEMBL27521765 0.75 MEN1 (0.41) MEN1KMT2AALDH1A1LMNAMAPT
SCHEMBL10636182 0.72 HPGD (0.36) MEN1KMT2ACYP2C19CYP1A2SMN1; SMN2
SCHEMBL9225690 0.72 KMT2A (0.55) MEN1KMT2AALDH1A1LMNAMAPT
SCHEMBL8153357 0.72 KMT2A (0.47) MEN1KMT2AALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3122448-B1 DISPERSIONS CONTAINING ENCAPSULATED MATERIALS AND COMPOSITIONS USING SAME NUSIL TECH LLC (US) 2020-12-09 EP disclosed
US-20190209447-A1 SURFACTANT FREE SILICONE EMULSION NUSIL TECHNOLOGY LLC 2019-07-11 US disclosed
EP-3443025-A1 SURFACTANT FREE SILICONE EMULSION Nusil Technology LLC (US) 2019-02-20 EP disclosed
US-10206859-B2 Cosmetic composition THE PROCTER & GAMBLE COMPANY (US) 2019-02-19 US disclosed
EP-3302410-A1 MULTI-COMPONENT PRODUCTS AND MULTI-STEP REGIMENS FOR IMPROVING THE APPEARANCE OR FEEL OF HUMAN SKIN The Procter and Gamble Company (US) 2018-04-11 EP disclosed
WO-2017180567-A1 SURFACTANT FREE SILICONE EMULSION NUSIL TECHNOLOGY LLC (US) 2017-10-19 WO disclosed
EP-2385819-B1 SILICONE PASTE COMPOSITIONS DOW CORNING (US) 2017-06-28 EP disclosed
EP-3174520-A1 COSMETIC COMPOSITION The Procter and Gamble Company (US) 2017-06-07 EP disclosed
EP-3174604-A1 A MULTI-STEP REGIMEN FOR IMPROVING THE APPEARANCE AND FEEL OF HUMAN SKIN The Procter and Gamble Company (US) 2017-06-07 EP disclosed
EP-3122448-A1 DISPERSIONS CONTAINING ENCAPSULATED MATERIALS AND COMPOSITIONS USING SAME Nusil Technology LLC (US) 2017-02-01 EP disclosed
EP-1507507-A2 SUBSTITUTED HYDROCARBYL FUNCTIONAL SILOXANES FOR HOUSEHOLD, HEALTH, AND PERSONAL CARE APPLICATIONS Dow Corning Corporation (US) 2005-02-23 EP disclosed
US-20040223936-A1 Substituted hydrocarbyl functional siloxanes for household, health, and personal care applications DOW CORNING S.A. (BE) 2004-11-11 US disclosed
US-20040197285-A1 Sunscreens based on substituted hydrocarbyl functional siloxanes for household, health, and personal care applications DOW CORNING CORPORATION 2004-10-07 US disclosed
WO-2004009662-A1 COPOLYMERS AND THEIR USE IN PERSONAL CARE COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-01-29 WO disclosed
WO-2003101412-A2 SUBSTITUTED HYDROCARBYL FUNCTIONAL SILOXANES FOR HOUSEHOLD, HEALTH, AND PERSONAL CARE APPLICATIONS DOW CORNING CORPORATION (US) 2003-12-11 WO disclosed
US-20030228333-A1 Substituted hydrocarbyl functional siloxanes for household, health, and personal care applications DOW CORNING CORPORATION 2003-12-11 US disclosed
WO-2003051279-A2 TOPICAL COMPOSITIONS AND METHODS OF APPLICATION AVON PRODUCTS, INC. (US) 2003-06-26 WO disclosed
US-20030082129-A1 Hair and skin care compositions containing siloxane-based polyamide copolymers DOW CORNING CORPORATION 2003-05-01 US disclosed
US-6555095-B1 Containing a compound: L-A-H and A-L-H, wherein L is a lipophilic moiety, wherein A is an aromatic moiety having an ultraviolet absorption maximum between 290 nanometers and 400 nanometers, and wherein H is a hydrophilic moiety AVON PRODUCTS, INC. 2003-04-29 US disclosed
WO-2003013447-A2 HAIR AND SKIN CARE COMPOSITIONS CONTAINING SILOXANE-BASED POLYAMIDE COPOLYMERS DOW CORNING CORPORATION (US) 2003-02-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10206859-B2 Cosmetic composition CUTA, DEGS1, UGCG MEN1 433/4885KMT2A 4510/4885ALDH1A1 3472/4885
US-20030082129-A1 Hair and skin care compositions containing siloxane-based polyamide copolymers CUTA, POLR1C, KRT18 MEN1 2257/4885KMT2A 650/4885ALDH1A1 2761/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.