SCHEMBL2903789

SCHEMBL2903789

CC1(C)C2CCC1(C=C(c1ccccc1)S(=O)(=O)O)C(=O)C2

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.42
CYP2C19 P33261 2/20 0.42
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
KMT2A Q03164 5/20 0.37
MEN1 O00255 4/20 0.37
ALDH1A1 P00352 2/20 0.37
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
KDM4E B2RXH2 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
TSHR P16473 1/20 0.35
HSD17B10 Q99714 1/20 0.35
F2 P00734 1/20 0.34
PRSS1 P07477 1/20 0.34
PRSS2 P07478 1/20 0.34
PRSS3 P35030 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19421 0.83 MEN1 (0.41) CYP1A2CYP2C19CYP2D6CYP2C9KMT2A
SCHEMBL6553778 0.82 CYP1A2 (0.42) CYP1A2CYP2C19CYP2D6CYP2C9KMT2A
SCHEMBL150729 0.82 MEN1 (0.41) CYP1A2CYP2C19CYP2D6CYP2C9KMT2A
SCHEMBL1768748 0.79 CYP1A2 (0.40) CYP1A2CYP2C19CYP2D6CYP2C9KMT2A
Methylamine SCHEMBL27521765 0.73 MEN1 (0.41) CYP1A2CYP2C19CYP2D6CYP2C9KMT2A
SCHEMBL20455791 0.72 KMT2A (0.44) CYP1A2CYP2C19CYP2D6CYP2C9KMT2A
SCHEMBL345420 0.71 TRPM8 (0.37) CYP1A2CYP2C19ALDH1A1LMNA
SCHEMBL44530 0.68 CYP2C19 (0.42) CYP1A2CYP2C19CYP2D6CYP2C9KMT2A
Camphor SCHEMBL27571091 0.68 MEN1 (0.61) CYP1A2CYP2C19CYP2D6CYP2C9KMT2A
SCHEMBL10636182 0.68 HPGD (0.36) CYP1A2CYP2C19KMT2AMEN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109069384-B 10-hydroxystearic acid composition 帝斯曼知识产权资产管理有限公司 2022-10-18 CN disclosed
CN-109069381-B 10-hydroxystearic acid composition 帝斯曼知识产权资产管理有限公司 2021-11-30 CN disclosed
CN-107072902-B Use of cosmetic compositions comprising 10-hydroxystearic acid 帝斯曼知识产权资产管理有限公司 2021-01-19 CN disclosed
EP-1494642-B1 Organosilicon derivatives of aminohydroxybenzophenones and their use as UV-A filters in cosmetic preparations DSM IP ASSETS BV (NL) 2010-03-10 EP disclosed
US-7611696-B2 Sunscreen compositions as well as dihydropyridines and dihydropyranes DSM IP ASSETS B.V. (NL) 2009-11-03 US disclosed
US-7388102-B2 Organosilicone derivatives of amino hydroxybenzophenones and their use as UV-A filters in cosmetic preparations DSM IP ASSETS B.V. (NL) 2008-06-17 US disclosed
US-20080031909-A1 Encapsulated Cosmetic Materials DSM IP ASSETS B.V. (NL) 2008-02-07 US disclosed
US-20070270472-A1 Amino, Amino Acid or Peptide Conjugates of Retinoic Acid DSM IP ASSETS B.V. (NL) 2007-11-22 US disclosed
EP-1838428-A1 ENCAPSULATED COSMETIC MATERIALS DSMIP Assets B.V. (NL) 2007-10-03 EP disclosed
EP-1765773-A2 AMINO, AMINO ACID OR PEPTIDE CONJUGATES OF RETINOIC ACID DSMIP Assets B.V. (NL) 2007-03-28 EP disclosed
EP-1474098-B1 SUNSCREEN COMPOSITIONS AS WELL AS DIHYDROPYRIDINES AND DIHYDROPYRANES DSM IP ASSETS BV (NL) 2006-08-02 EP disclosed
WO-2006061124-A1 ENCAPSULATED COSMETIC MATERIALS DSM IP ASSETS B.V. (NL) 2006-06-15 WO disclosed
WO-2006005455-A2 AMINO, AMINO ACID OR PEPTIDE CONJUGATES OF RETINOIC ACID DSM IP ASSETS B.V. (NL) 2006-01-19 WO disclosed
US-20050255066-A1 Organosilicone derivatives of amino hydroxybenzophenones and their use as uv-a filters in cosmetic preparations DSM NUTRITIONAL PRODUCTS LTD F/K/A ROCHE VITAMINS AG (CH) 2005-11-17 US disclosed
US-20050019278-A1 Sunscreen compositions as well as dihydropyridines and dihydropyranes ROCHE VITAMINS AG (CH) 2005-01-27 US disclosed
EP-1474098-A1 SUNSCREEN COMPOSITIONS AS WELL AS DIHYDROPYRIDINES AND DIHYDROPYRANES DSM IP Assets B.V. (NL) 2004-11-10 EP disclosed
WO-2003068183-A1 SUNSCREEN COMPOSITIONS AS WELL AS DIHYDROPYRIDINES AND DIHYDROPYRANES DSM IP ASSETS B.V. (NL) 2003-08-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070270472-A1 Amino, Amino Acid or Peptide Conjugates of Retinoic Acid RARA, RARG, RARB CYP1A2 4405/4885CYP2C19 4653/4885CYP2D6 4695/4885
US-20050255066-A1 Organosilicone derivatives of amino hydroxybenzophenones and their use as uv-a filters in cosmetic preparations CUTA, TYR, ERCC5 CYP1A2 450/4885CYP2C19 364/4885CYP2D6 710/4885
US-20050019278-A1 Sunscreen compositions as well as dihydropyridines and dihydropyranes DHPS, DSG1, DHODH CYP1A2 515/4885CYP2C19 1130/4885CYP2D6 483/4885
US-20080031909-A1 Encapsulated Cosmetic Materials H1-5, ADGRE5, KAT5 CYP1A2 1915/4885CYP2C19 1625/4885CYP2D6 2096/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.