SCHEMBL19421990

SCHEMBL19421990

COc1cc(C(c2cc(CO)c(O)c(CO)c2)(C(F)(F)F)C(F)(F)F)cc(CO)c1O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.40
PDE4B Q07343 1/20 0.40
PDE4C Q08493 1/20 0.40
PDE4D Q08499 1/20 0.40
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
ALOX5 P09917 5/20 0.36
PTGS2 P35354 4/20 0.35
TNKS2 Q9H2K2 1/20 0.34
ERN1 O75460 2/20 0.34
ALOX15 P16050 1/20 0.34
MCL1 Q07820 1/20 0.34
KLF10 Q13118 1/20 0.33
KDM4E B2RXH2 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA3 P07451 1/20 0.32
PKM P14618 1/20 0.32
CA4 P22748 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2466723 0.85 ESR1 (0.41) ALOX15KLF10KDM4EESR1ESR2
SCHEMBL9764127 0.83 PKM (0.44) GAAMAPTALOX5PTGS2ERN1
SCHEMBL10130971 0.82 ALOX15 (0.47) PDE4APDE4BPDE4CPDE4DGAA
SCHEMBL10130844 0.81 PDE4A (0.42) PDE4APDE4BPDE4CPDE4DGAA
SCHEMBL12134641 0.81 ALOX15 (0.46) PDE4APDE4BPDE4CPDE4DGAA
SCHEMBL10130843 0.80 CYP2C19 (0.44) PDE4APDE4BPDE4CPDE4DALOX5
SCHEMBL10064214 0.79 ALOX15 (0.47) PDE4APDE4BPDE4CPDE4DGAA
SCHEMBL19410100 0.78 SHBG (0.52) PTGS2ALOX15KLF10KDM4ECA1
SCHEMBL15856231 0.76 IDO1 (0.41) ESR1ESR2
SCHEMBL12261394 0.75 PDE4A (0.40) PDE4APDE4BPDE4CPDE4DGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170285474-A1 PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE RESIN LAMINATE, RESIN PATTERN PRODUCTION METHOD, CURED FILM, AND DISPLAY DEVICE ASAHI KASEI KABUSHIKI KAISHA (JP) 2017-10-05 US disclosed