SCHEMBL194290

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29815746	1.00	CYP1A2 (0.54)	CYP1A2CYP3A4CYP2C9CYP2C19MAP2K1
	SCHEMBL193958	0.83	KDM4E (0.41)	MAP2K1MAP2K2ALDH1A1KDM4EKMT2A
	SCHEMBL29815961	0.83	PGR (0.46)	MAP2K1MAP2K2ALDH1A1KDM4EKMT2A
	SCHEMBL194369	0.83	PGR (0.46)	MAP2K1MAP2K2ALDH1A1KDM4EKMT2A
	SCHEMBL29815772	0.83	KDM4E (0.41)	MAP2K1MAP2K2ALDH1A1KDM4EKMT2A
	SCHEMBL194587	0.80	KDM4E (0.49)	CYP1A2CYP3A4CYP2C9CYP2C19MAP2K1
	SCHEMBL194441	0.78	ATM (0.50)	ALDH1A1KDM4EKMT2ARXFP1MAPT
	SCHEMBL193973	0.77	USP7 (0.42)	CYP1A2CYP3A4CYP2C9CYP2C19ALDH1A1
	SCHEMBL29816147	0.77	USP7 (0.42)	CYP1A2CYP3A4CYP2C9CYP2C19ALDH1A1
	SCHEMBL194725	0.75	ALDH1A1 (0.54)	ALDH1A1KDM4EKMT2ARXFP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.