SCHEMBL194587

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29816227	0.83	MAP2K2 (0.60)	KDM4EALDH1A1MAPTMAOAMAOB
	SCHEMBL194258	0.83	CDC7 (0.46)	KDM4EALDH1A1MAPTHPGDKMT2A
	SCHEMBL194257	0.83	MAP2K2 (0.60)	KDM4EALDH1A1MAPTMAOAMAOB
	SCHEMBL193704	0.80	CYP19A1 (0.47)	ALDH1A1MAPTHPGDMAOAMAOB
	SCHEMBL194290	0.80	CYP1A2 (0.54)	KDM4EALDH1A1MAPTHPGDMAP2K2
	SCHEMBL29815746	0.80	CYP1A2 (0.54)	KDM4EALDH1A1MAPTHPGDMAP2K2
	SCHEMBL194441	0.78	ATM (0.50)	KDM4EALDH1A1MAPTHPGDMCL1
	SCHEMBL194493	0.78	MAOA (0.41)	KDM4EALDH1A1MAPTHPGDMCL1
	SCHEMBL194725	0.75	ALDH1A1 (0.54)	KDM4EALDH1A1MAPTHPGDMCL1
	SCHEMBL194369	0.74	PGR (0.46)	KDM4EALDH1A1MAPTHPGDMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.