SCHEMBL194386

SCHEMBL194386

COc1nnc(OC)c2cc[c]cc12

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.56
CYP1A2 P05177 1/20 0.56
CYP2C19 P33261 1/20 0.56
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL193991 0.76 ALDH1A1 (0.38) ALDH1A1CYP1A2CYP2C19NPC1RAB9A
SCHEMBL2724218 0.72 ALDH1A1 (1.00) ALDH1A1CYP1A2CYP2C19NPC1RAB9A
SCHEMBL2304546 0.71 CNR1 (0.38) ALDH1A1CYP1A2CYP2C19
SCHEMBL1402281 0.70 IMPDH2 (0.42)
SCHEMBL6358224 0.69 ALDH1A1 (0.31) ALDH1A1CYP1A2CYP2C19
SCHEMBL15515308 0.69 MAPT (0.37) ALDH1A1CYP1A2CYP2C19SMN1; SMN2L3MBTL1
SCHEMBL2302738 0.69 CNR1 (0.37) ALDH1A1CYP1A2CYP2C19
SCHEMBL15515042 0.68 GRM4 (0.33) ALDH1A1CYP1A2CYP2C19
SCHEMBL193961 0.67 KMT2A (0.34) ALDH1A1CYP1A2CYP2C19NPC1RAB9A
SCHEMBL12215453 0.64 ALDH1A1 (0.78) ALDH1A1CYP1A2CYP2C19NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 189 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8652752-B2 Sulphonium salt initiators BASF SE (DE) 2014-02-18 US claimed
EP-2197840-B1 SULPHONIUM SALT INITIATORS BASF SE (DE) 2013-11-06 EP claimed
CN-101952269-A Sulphonium salt initiators BASF SE 2011-01-19 CN claimed
US-20100297540-A1 SULPHONIUM SALT INITIATORS BASF SE (DE) 2010-11-25 US claimed
CN-115504896-B Acrylic formate compound for LED photopolymerization, preparation method and application thereof 湖北固润科技股份有限公司 2024-05-07 CN disclosed
WO-2024078413-A1 ACRYLOYL FORMATE COMPOUND FOR LED PHOTOPOLYMERIZATION, AND PREPARATION METHOD THEREFOR AND USE THEREOF 湖北固润科技股份有限公司 2024-04-18 WO disclosed
CN-107463067-B Black photosensitive resin composition and application thereof 奇美实业股份有限公司 2024-01-26 CN disclosed
CN-117142995-A Pyruvic acid (hetero) arylthioester compound for LED photopolymerization and preparation and application thereof 湖北固润科技股份有限公司 2023-12-01 CN disclosed
CN-117142994-A Amphiphilic polyether alpha-ketone (hetero) arylthioester compound for LED photopolymerization and preparation and application thereof 湖北固润科技股份有限公司 2023-12-01 CN disclosed
US-20230142648-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2023-05-11 US disclosed
EP-4114825-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2023-01-11 EP disclosed
CN-115210219-A Oxime ester photoinitiators 巴斯夫欧洲公司 2022-10-18 CN disclosed
WO-1998055543-A1 POLYMER STABILIZATION DYNEON LLC (US) 1998-12-10 WO disclosed
US-5814692-A PROTECTING POLYMERS AND LUBRICANTS AGAINST THERMAL, OXIDATIVE OR LIGHT-INDUCED DEGRADATION CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-09-29 US disclosed
EP-0857765-A2 Stabilizing agents for powder paints Ciba SC Holding AG (CH) 1998-08-12 EP disclosed
US-5773631-A PROTECTION OF POLYMERS AND LUBRICANTS AGAINST THERMAL, OXIDATIVE OR LIGHT INDUCED DEGRDATION CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-06-30 US disclosed
EP-0842975-A1 Stabilising polyolefins for long term contact with an extracting medium Ciba SC Holding AG (CH) 1998-05-20 EP disclosed
EP-0839623-A1 Stabiliser combination for rotomolding process Ciba SC Holding AG (CH) 1998-05-06 EP disclosed
CN-1172176-A Phenol-free stabilization of polyolefin fibres CIBA SC HOLDING AG (CH) 1998-02-04 CN disclosed
US-5516920-A POLYMER STABILIZERS CIBA-GEIGY CORPORATION (US) 1996-05-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100297540-A1 SULPHONIUM SALT INITIATORS SULT1A1, SULT2A1, NCOA1 ALDH1A1 1081/4885CYP1A2 2387/4885CYP2C19 3638/4885
US-20230142648-A1 OXIME ESTER PHOTOINITIATORS OCIAD1, OCIAD2, OXER1 ALDH1A1 964/4885CYP1A2 493/4885CYP2C19 165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.