SCHEMBL193991

SCHEMBL193991

COc1nncc2c[c]ccc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
CYP1A2 P05177 2/20 0.38
CYP2C19 P33261 1/20 0.38
KDM4E B2RXH2 2/20 0.32
TP53 P04637 2/20 0.32
CYP3A4 P08684 2/20 0.32
GOT1 P17174 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
NPC1 O15118 1/20 0.32
LMNA P02545 1/20 0.32
MPO P05164 1/20 0.32
CYP2D6 P10635 1/20 0.32
PKM P14618 1/20 0.32
MAOA P21397 1/20 0.32
PTGS1 P23219 1/20 0.32
THPO P40225 1/20 0.32
RAB9A P51151 1/20 0.32
AOX1 Q06278 1/20 0.32
ACOX1 Q15067 1/20 0.32
SOS1 Q07889 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL194386 0.76 ALDH1A1 (0.56) ALDH1A1CYP1A2CYP2C19SMN1; SMN2NPC1
SCHEMBL29674926 0.74 ALDH1A1 (0.59) ALDH1A1CYP1A2CYP2C19KDM4ETP53
SCHEMBL8809641 0.74 ALDH1A1 (0.59) ALDH1A1CYP1A2CYP2C19KDM4ETP53
SCHEMBL15515308 0.74 MAPT (0.37) ALDH1A1CYP1A2CYP2C19CYP3A4SMN1; SMN2
SCHEMBL6358224 0.74 ALDH1A1 (0.31) ALDH1A1CYP1A2CYP2C19
SCHEMBL4301481 0.73
SCHEMBL2856946 0.73 C1S (0.38) ALDH1A1CYP1A2KDM4ETP53CYP3A4
SCHEMBL13763666 0.70 C1S (0.44) ALDH1A1CYP1A2CYP2C19CYP3A4SMN1; SMN2
SCHEMBL193961 0.64 KMT2A (0.34) ALDH1A1CYP1A2CYP2C19KDM4ESMN1; SMN2
SCHEMBL13271043 0.64 RAB9A (0.45) ALDH1A1CYP1A2CYP2C19NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8652752-B2 Sulphonium salt initiators BASF SE (DE) 2014-02-18 US claimed
EP-2197840-B1 SULPHONIUM SALT INITIATORS BASF SE (DE) 2013-11-06 EP claimed
US-20100297540-A1 SULPHONIUM SALT INITIATORS BASF SE (DE) 2010-11-25 US claimed
EP-2197869-A1 SULPHONIUM SALT INITIATORS BASF SE (DE) 2010-06-23 EP claimed
WO-2009047105-A1 SULPHONIUM SALT INITIATORS BASF SE (CH) 2009-04-16 WO claimed
CN-115504896-B Acrylic formate compound for LED photopolymerization, preparation method and application thereof 湖北固润科技股份有限公司 2024-05-07 CN disclosed
WO-2024078413-A1 ACRYLOYL FORMATE COMPOUND FOR LED PHOTOPOLYMERIZATION, AND PREPARATION METHOD THEREFOR AND USE THEREOF 湖北固润科技股份有限公司 2024-04-18 WO disclosed
CN-107463067-B Black photosensitive resin composition and application thereof 奇美实业股份有限公司 2024-01-26 CN disclosed
CN-117142994-A Amphiphilic polyether alpha-ketone (hetero) arylthioester compound for LED photopolymerization and preparation and application thereof 湖北固润科技股份有限公司 2023-12-01 CN disclosed
CN-117142995-A Pyruvic acid (hetero) arylthioester compound for LED photopolymerization and preparation and application thereof 湖北固润科技股份有限公司 2023-12-01 CN disclosed
US-20230142648-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2023-05-11 US disclosed
CN-115210219-A Oxime ester photoinitiators 巴斯夫欧洲公司 2022-10-18 CN disclosed
WO-1998041524-A1 PHOTOACTIVATABLE NITROGEN-CONTAINING BASES BASED ON α-AMINO ALKENES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1998-09-24 WO disclosed
WO-1998038195-A1 PHOTOACTIVATABLE NITROGEN-CONTAINING BASES BASED ON α-AMMONIUM KETONES, IMINIUM KETONES OR AMIDINIUM KETONES AND ARYL BORATES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1998-09-03 WO disclosed
EP-0857765-A2 Stabilizing agents for powder paints Ciba SC Holding AG (CH) 1998-08-12 EP disclosed
WO-1998032756-A1 SUBSTITUTED AMINOALKYLIDENAMINO TRIAZINES AS HERBICIDES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1998-07-30 WO disclosed
US-5773631-A PROTECTION OF POLYMERS AND LUBRICANTS AGAINST THERMAL, OXIDATIVE OR LIGHT INDUCED DEGRDATION CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-06-30 US disclosed
EP-0842975-A1 Stabilising polyolefins for long term contact with an extracting medium Ciba SC Holding AG (CH) 1998-05-20 EP disclosed
EP-0839623-A1 Stabiliser combination for rotomolding process Ciba SC Holding AG (CH) 1998-05-06 EP disclosed
US-5516920-A POLYMER STABILIZERS CIBA-GEIGY CORPORATION (US) 1996-05-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100297540-A1 SULPHONIUM SALT INITIATORS SULT1A1, SULT2A1, NCOA1 ALDH1A1 1081/4885CYP1A2 2387/4885CYP2C19 3638/4885
US-20230142648-A1 OXIME ESTER PHOTOINITIATORS OCIAD1, OCIAD2, OXER1 ALDH1A1 964/4885CYP1A2 493/4885CYP2C19 165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.